Background: The hypothesis of the existence of a Lung Cancer Initiating Cell (LCIC) offers new pathogenetic and therapeutic options. CICs express vascular-related molecules in order to induce neoangiogenesis and establish an aberrant vascular niche. Conversely, tumor angiogenesis and formation of a cancer vascular niche contribute to the maintenance of CIC. The limited success of anti-angiogenic strategies in lung cancer imposes a better knowledge of the biology and architecture of the tumor vascular microenvironment. The aim of our study was to characterize the structural and functional changes of blood and lymphatic vasculature in human lung cancer. Methods: Fresh samples of the neoplastic(T) and spared distal (Dist) lung from 30 p...
BACKGROUND: We have recently shown the prognostic value of growth pattern classification in non-smal...
Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mo...
Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mo...
Background: The hypothesis of the existence of a Lung Cancer Initiating Cell (LCIC) offers new patho...
OBJECTIVES: Lymphangiogenesis plays a critical role in the immune response, tumour progression and ...
Lung cancer usually forms from cells that line the airways and nearby glands since these cells come ...
Until recently, it was generally accepted that vascularization of tumors arises exclusively from e...
Background : Tumor angiogenesis is the growth of new vessels toward and within tumor. It has been de...
IntroductionAngiogenesis plays a significant role in tumor progression. This study examined the asso...
the pathogenesis and management of lung cancer. A relevant component of the niche is represented by...
Abstract Purpose:Recent experimental studies have revealed that lymphangiogenesis plays an important...
Lung cancer represents one of the most frequent causes of death due to neoplastic disease in Poland ...
Angiogenesis has long been considered an essential prerequisite for tumour growth and progression. H...
This study investigated the clinicopathologic correlation of tumor angiogene-sis in non-small cell l...
Characterization of lymphatic endothelial cells from the respiratory system may be crucial to invest...
BACKGROUND: We have recently shown the prognostic value of growth pattern classification in non-smal...
Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mo...
Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mo...
Background: The hypothesis of the existence of a Lung Cancer Initiating Cell (LCIC) offers new patho...
OBJECTIVES: Lymphangiogenesis plays a critical role in the immune response, tumour progression and ...
Lung cancer usually forms from cells that line the airways and nearby glands since these cells come ...
Until recently, it was generally accepted that vascularization of tumors arises exclusively from e...
Background : Tumor angiogenesis is the growth of new vessels toward and within tumor. It has been de...
IntroductionAngiogenesis plays a significant role in tumor progression. This study examined the asso...
the pathogenesis and management of lung cancer. A relevant component of the niche is represented by...
Abstract Purpose:Recent experimental studies have revealed that lymphangiogenesis plays an important...
Lung cancer represents one of the most frequent causes of death due to neoplastic disease in Poland ...
Angiogenesis has long been considered an essential prerequisite for tumour growth and progression. H...
This study investigated the clinicopathologic correlation of tumor angiogene-sis in non-small cell l...
Characterization of lymphatic endothelial cells from the respiratory system may be crucial to invest...
BACKGROUND: We have recently shown the prognostic value of growth pattern classification in non-smal...
Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mo...
Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mo...