International audienceXenopus cyclin D2 mRNA is a member of the class of maternal RNAs. It is rare and stable during early embryonic development. To investigate the potential role of cyclin D2 during early embryonic cell cycles, cyclin D2 was injected into one blastomere of a two-cell embryo. This injection induced a cell cycle arrest in the injected blastomere. To analyze more precisely the mechanism of this arrest, we took advantage of cycling egg extracts that recapitulate major events of the cell cycle when supplemented with demembranated sperm heads. When Xenopus cyclin D2 is added to egg extracts, the first round of DNA replication occurs as in control extracts. However, Xenopus cyclin D2 blocks subsequent rounds of DNA replication an...
Cyclins and cyclin dependent kinases (Cdk) are key regulators of the cell cycle. Cyclin E binds to a...
"The cyclin-dependent kinase (Cdk1) oscillator has been widely characterized in bulk xenopus egg ext...
The early embryonic Xenopus cell cycles are characterized by alternating oscillations of Cyclin-depe...
International audienceXenopus cyclin D2 mRNA is a member of the class of maternal RNAs. It is rare a...
AbstractWe report here the first extensivein vivostudy of cell cycle regulation in theXenopusembryo....
AbstractIn mammalian cells, E-type cyclins (E1 and E2) are generally believed to be required for ent...
AbstractIn the early embryonic cell cycle, exit from M phase is immediately followed by entry into S...
Extracts of activated Xenopus eggs in which protein synthesis has been inhibited support a single ro...
AbstractDuringXenopusdevelopment, the early cell cycles consist of rapid oscillations between DNA sy...
Early Xenopus laevis embryonic cell cycles exemplify rapid, non-pathological cell cycles without che...
Activation of Cdc2/cyclin B kinase and entry into mitosis requires dephosphorylation of inhibitory s...
INTRODUCTION: The processes of cell proliferation and cell death are intimately linked. In many situ...
International audienceAt the midblastula transition, the Xenopus laevis embryonic cell cycle is remo...
Cell division and differentiation are largely incompatible but the molecular links between the two p...
Cyclins and cyclin dependent kinases (Cdk) are key regulators of the cell cycle. Cyclin E binds to a...
"The cyclin-dependent kinase (Cdk1) oscillator has been widely characterized in bulk xenopus egg ext...
The early embryonic Xenopus cell cycles are characterized by alternating oscillations of Cyclin-depe...
International audienceXenopus cyclin D2 mRNA is a member of the class of maternal RNAs. It is rare a...
AbstractWe report here the first extensivein vivostudy of cell cycle regulation in theXenopusembryo....
AbstractIn mammalian cells, E-type cyclins (E1 and E2) are generally believed to be required for ent...
AbstractIn the early embryonic cell cycle, exit from M phase is immediately followed by entry into S...
Extracts of activated Xenopus eggs in which protein synthesis has been inhibited support a single ro...
AbstractDuringXenopusdevelopment, the early cell cycles consist of rapid oscillations between DNA sy...
Early Xenopus laevis embryonic cell cycles exemplify rapid, non-pathological cell cycles without che...
Activation of Cdc2/cyclin B kinase and entry into mitosis requires dephosphorylation of inhibitory s...
INTRODUCTION: The processes of cell proliferation and cell death are intimately linked. In many situ...
International audienceAt the midblastula transition, the Xenopus laevis embryonic cell cycle is remo...
Cell division and differentiation are largely incompatible but the molecular links between the two p...
Cyclins and cyclin dependent kinases (Cdk) are key regulators of the cell cycle. Cyclin E binds to a...
"The cyclin-dependent kinase (Cdk1) oscillator has been widely characterized in bulk xenopus egg ext...
The early embryonic Xenopus cell cycles are characterized by alternating oscillations of Cyclin-depe...