Add to ORKGThe present invention relates to calixarene derivatives functionalized at the upper and lower rim with arginine or guanidinylated amino acid units through proper variable spacers. The compounds of the invention interact with and non-covalently bind to nucleic acids, condense and transport them inside cells. These compounds can be used as non-viral vectors for cell transfection
Gene therapy is a technique that is currently under expansion and development. Recent advances in ge...
Calixarenes are versatile platforms for the design and synthesis of molecular receptors and multival...
Calix[n]arenes functionalized with guanidinium groups at the upper rim and alkyl chains at the lower...
© 2015 Nova Science Publishers, Inc. Targeted delivery of polynucleic acids in cells (transfection) ...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone c...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone ...
A rapid synthetic route to a nontoxic fluorescently labeled water-soluble calixarene has been develo...
New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transf...
The cell membrane plays important roles of protection and support, it regulates the transport of sub...
A new bimodal fluorescent cationic calix[4]arene (L-1) conjugate has been synthesized in multiple st...
A rapid synthetic route to a nontoxic fluorescently labeled water-soluble calixarene has been develo...
Thanks to their specific structural features and a wide variety of functionalization options, in the...
Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, ...
Cell-penetrating peptides are widely used as molecular transporters for the internalization inside c...
The application of Peptide Nucleic Acids (PNAs), mimics of DNA lacking the sugar-phosphate backbone,...
Gene therapy is a technique that is currently under expansion and development. Recent advances in ge...
Calixarenes are versatile platforms for the design and synthesis of molecular receptors and multival...
Calix[n]arenes functionalized with guanidinium groups at the upper rim and alkyl chains at the lower...
© 2015 Nova Science Publishers, Inc. Targeted delivery of polynucleic acids in cells (transfection) ...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone c...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone ...
A rapid synthetic route to a nontoxic fluorescently labeled water-soluble calixarene has been develo...
New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transf...
The cell membrane plays important roles of protection and support, it regulates the transport of sub...
A new bimodal fluorescent cationic calix[4]arene (L-1) conjugate has been synthesized in multiple st...
A rapid synthetic route to a nontoxic fluorescently labeled water-soluble calixarene has been develo...
Thanks to their specific structural features and a wide variety of functionalization options, in the...
Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, ...
Cell-penetrating peptides are widely used as molecular transporters for the internalization inside c...
The application of Peptide Nucleic Acids (PNAs), mimics of DNA lacking the sugar-phosphate backbone,...
Gene therapy is a technique that is currently under expansion and development. Recent advances in ge...
Calixarenes are versatile platforms for the design and synthesis of molecular receptors and multival...
Calix[n]arenes functionalized with guanidinium groups at the upper rim and alkyl chains at the lower...