This review aims at providing a critical assessment of the effects of the most widely used benzodiazepine (flurazepam, flunitrazepam, temazepam, triazolam) and non-benzodiazepine (zopiclone and zolpidem) hypnotic drugs, based on the recording of polysomnographic variables. In the light of newly acquired neurophysiological data on the microstructure of sleep, this paper reconsiders the problem of insomnia and the current ideas on polysomnography and hypnotic drugs
BACKGROUND AND PURPOSE: Treatment of chronic insomnia with nightly hypnotics is efficacious, but dis...
IntroductionInsomnia is a stress-related sleep disorder, may favor a state of allostatic overload im...
Sleep disorders are not uncommon and have been widely reported throughout the world. They have a pro...
Since homogeneous samples of insomniacs are difficult to recruit for pharmacotherapy studies, normal...
The Cyclic Alternating Pattern (CAP) is an intrinsic component of normal NREM sleep. This periodic a...
In nonrapid eye movement (NREM) sleep, electroencephalographic cyclic alternating patterns (CAPS) ex...
Polysomnography (PSG) is considered the gold standard for diagnosis of non-rapid eye movement (NREM)...
OBJECTIVE: Polysomnographic (PSG) measures consistently reflect poor sleep quality and effective tre...
peer reviewedBenzodiazepines currently represent the most widely prescribed family of hypnotic drugs...
This chapter summarises the most important principles of sleep physiology and pharmacology, which ho...
Insomnia is a prevalent disorder with deleterious effects such as decreased quality of life, and a p...
The effect of psychoactive drugs on sleep is traditionally evaluated with polysomnography (PSG) wher...
Zolpidem, zopiclone and zaleplon are hypnotics with similar pharmacology to benzodiazepines. In addi...
The standardized scoring criteria of sleep can serve as a rough tool for monitoring the effects of p...
Six middle aged subjects complaining of chronic insomnia associated with dysthymia were investigated...
BACKGROUND AND PURPOSE: Treatment of chronic insomnia with nightly hypnotics is efficacious, but dis...
IntroductionInsomnia is a stress-related sleep disorder, may favor a state of allostatic overload im...
Sleep disorders are not uncommon and have been widely reported throughout the world. They have a pro...
Since homogeneous samples of insomniacs are difficult to recruit for pharmacotherapy studies, normal...
The Cyclic Alternating Pattern (CAP) is an intrinsic component of normal NREM sleep. This periodic a...
In nonrapid eye movement (NREM) sleep, electroencephalographic cyclic alternating patterns (CAPS) ex...
Polysomnography (PSG) is considered the gold standard for diagnosis of non-rapid eye movement (NREM)...
OBJECTIVE: Polysomnographic (PSG) measures consistently reflect poor sleep quality and effective tre...
peer reviewedBenzodiazepines currently represent the most widely prescribed family of hypnotic drugs...
This chapter summarises the most important principles of sleep physiology and pharmacology, which ho...
Insomnia is a prevalent disorder with deleterious effects such as decreased quality of life, and a p...
The effect of psychoactive drugs on sleep is traditionally evaluated with polysomnography (PSG) wher...
Zolpidem, zopiclone and zaleplon are hypnotics with similar pharmacology to benzodiazepines. In addi...
The standardized scoring criteria of sleep can serve as a rough tool for monitoring the effects of p...
Six middle aged subjects complaining of chronic insomnia associated with dysthymia were investigated...
BACKGROUND AND PURPOSE: Treatment of chronic insomnia with nightly hypnotics is efficacious, but dis...
IntroductionInsomnia is a stress-related sleep disorder, may favor a state of allostatic overload im...
Sleep disorders are not uncommon and have been widely reported throughout the world. They have a pro...