During the last decade, a significant body of evidence has accumulated, indicating that the declining activity of the GH-IGF-I axis with aging might play a role in the development of frailty and in several pathological conditions commonly seen during aging, such as atherosclerosis, cardiovascular disease, and cognitive decline. GH therapy has become widely popular as antiaging therapy in order to counteract the age-related decline in muscle mass and strength and the increase in fat mass. However there are only few proven beneficial effects of GH therapy in healthy elderly subjects and its use remains highly controversial in the scientific community. In this paper we will review the current evidence related to the use of ...
During the last decade, a significant body of evidence has accumulated, indicating that IGF-I might...
Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice mo...
The widespread increase in life expectancy is accompanied by an increased prevalence of features of ...
Aging is associated with decay in the somatotroph axis, that has been considered to cause many of th...
Aging is associated with decline in the somatotroph axis, a decline that has been considered to caus...
The physiological changes that the human body undergoes during aging are similar to those observed i...
Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, an...
Many of the catabolic changes seen in normal aging, including osteopenia and sarcopenia, have been a...
Elizabeth C Hersch, George R MerriamVA Puget Sound Health Care System and University of Washington S...
Andrzej BartkeGeriatrics Research, Departments of Internal Medicine and Physiology, Southern Illinoi...
The somatotroph axis function shows a decline in the elderly (somatopause). In particular growth hor...
Is well being in the elderly be improved by hormone replacement therapy which compensate deficits ac...
Growth hormone (GH) use has been speculated to improve physical capacity in subjects without GH defi...
Aging is associated with progressive and substantial de-creases in growth hormone secretion and in c...
Improving physical function and mobility in a continuously expanding elderly population emerges as a...
During the last decade, a significant body of evidence has accumulated, indicating that IGF-I might...
Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice mo...
The widespread increase in life expectancy is accompanied by an increased prevalence of features of ...
Aging is associated with decay in the somatotroph axis, that has been considered to cause many of th...
Aging is associated with decline in the somatotroph axis, a decline that has been considered to caus...
The physiological changes that the human body undergoes during aging are similar to those observed i...
Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, an...
Many of the catabolic changes seen in normal aging, including osteopenia and sarcopenia, have been a...
Elizabeth C Hersch, George R MerriamVA Puget Sound Health Care System and University of Washington S...
Andrzej BartkeGeriatrics Research, Departments of Internal Medicine and Physiology, Southern Illinoi...
The somatotroph axis function shows a decline in the elderly (somatopause). In particular growth hor...
Is well being in the elderly be improved by hormone replacement therapy which compensate deficits ac...
Growth hormone (GH) use has been speculated to improve physical capacity in subjects without GH defi...
Aging is associated with progressive and substantial de-creases in growth hormone secretion and in c...
Improving physical function and mobility in a continuously expanding elderly population emerges as a...
During the last decade, a significant body of evidence has accumulated, indicating that IGF-I might...
Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice mo...
The widespread increase in life expectancy is accompanied by an increased prevalence of features of ...