New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transfection, have been obtained by attaching guanidinium groups at the lower rim of calix[4]arenes
Non–viral gene vectors exhibit several desirable properties, over their viral counterparts. This has...
We report herein the design, synthesis, and transfection biology of a novel series of non-glycerol-b...
The molecular structure of the cationic lipids used in gene transfection strongly influences their t...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone c...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone ...
The design of efficacious cationic transfection lipids with guanidinium headgroups is an actively pu...
Non-viral vectors such as cationic lipids are capable of delivering nucleic acids, including genes, ...
Non-viral vectors such as cationic lipids are capable of delivering nucleic acids, including genes, ...
The synthesis and in vitro evaluation of four cationic lipid gene delivery vectors, characterized by...
Calix[n]arenes functionalized with guanidinium groups at the upper rim and alkyl chains at the lower...
As a consequence of several setbacks encountered by viral technology in achieving efficient and safe...
The clinical success of gene therapy is critically dependent on the development of efficient and saf...
A promising strategy to design safer and more effective cationic lipids for gene delivery with inher...
International audienceOver the last several years, various gene delivery systems have been developed...
To obtain efficient non-viral vectors, a series of Gemini cationic lipids with carbamate linkers bet...
Non–viral gene vectors exhibit several desirable properties, over their viral counterparts. This has...
We report herein the design, synthesis, and transfection biology of a novel series of non-glycerol-b...
The molecular structure of the cationic lipids used in gene transfection strongly influences their t...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone c...
Guanidinium groups were introduced through a spacer at the lower rim of calix[4]arenes in the cone ...
The design of efficacious cationic transfection lipids with guanidinium headgroups is an actively pu...
Non-viral vectors such as cationic lipids are capable of delivering nucleic acids, including genes, ...
Non-viral vectors such as cationic lipids are capable of delivering nucleic acids, including genes, ...
The synthesis and in vitro evaluation of four cationic lipid gene delivery vectors, characterized by...
Calix[n]arenes functionalized with guanidinium groups at the upper rim and alkyl chains at the lower...
As a consequence of several setbacks encountered by viral technology in achieving efficient and safe...
The clinical success of gene therapy is critically dependent on the development of efficient and saf...
A promising strategy to design safer and more effective cationic lipids for gene delivery with inher...
International audienceOver the last several years, various gene delivery systems have been developed...
To obtain efficient non-viral vectors, a series of Gemini cationic lipids with carbamate linkers bet...
Non–viral gene vectors exhibit several desirable properties, over their viral counterparts. This has...
We report herein the design, synthesis, and transfection biology of a novel series of non-glycerol-b...
The molecular structure of the cationic lipids used in gene transfection strongly influences their t...
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