Background: Circadian rhythm disruption, sleep abnormalities, and shift work have emerged as cancer risk factors. Genetic variation of clock genes, which aid in circadian rhythm control, may increase cancer susceptibility or lead to disruption of hormone secretion. A Period 3 (Per3) clock gene variable number tandem repeat (VNTR) has been associated with chronotype, sleep and mood disturbances, altered hormone or cytokine secretion, and increased premenopausal breast cancer (BrCA) risk. Methods: Two studies were conducted. One study based in India identified histologically confirmed BrCA cases that were frequency-matched on age (+ 5 years), geographic region, menopausal status, and tim...
Circadian disruption has been linked with inflammation, an established cancer risk factor. Per3 cloc...
Introduction: Circadian disruption has been linked to carcinogenesis in animal models and to breast ...
Circadian clocks are fundamental, time-tracking systems that allow organisms to adapt to the appropr...
Background: Circadian rhythm disruption, sleep abnormalities, and shift work have emerged as...
Background: This study examined a PERIOD3 (PER3) gene variable number tandem repeat polymorphism and...
Polymorphisms in the PER3 gene have been associated with several human disease phenotypes, including...
International audienceNight shift work has been associated with an increased risk of breast cancer p...
Night shiftwork has been associated with an increased risk of breast cancer pointing to a role of ci...
Muurlink, OT ORCiD: 0000-0002-8251-9521The endogenous and self-sustained circadian rhythm generated ...
A major consequence of the world industrialized lifestyle is the increasing period of unnatural ligh...
A major consequence of the world industrialized lifestyle is the increasing period of unnatural ligh...
Objective To examine whether sleep traits have a causal effect on risk of breast cancer. Design Men...
Clock genes are expressed in a self-perpetuating, circadian pattern in virtually every tissue includ...
Background: Disruption of sleep patterns, and thereby the internal body clock, of shift workers dir...
Background: Circadian disruption is hypothesized to impact reproductive signaling, which in turn has...
Circadian disruption has been linked with inflammation, an established cancer risk factor. Per3 cloc...
Introduction: Circadian disruption has been linked to carcinogenesis in animal models and to breast ...
Circadian clocks are fundamental, time-tracking systems that allow organisms to adapt to the appropr...
Background: Circadian rhythm disruption, sleep abnormalities, and shift work have emerged as...
Background: This study examined a PERIOD3 (PER3) gene variable number tandem repeat polymorphism and...
Polymorphisms in the PER3 gene have been associated with several human disease phenotypes, including...
International audienceNight shift work has been associated with an increased risk of breast cancer p...
Night shiftwork has been associated with an increased risk of breast cancer pointing to a role of ci...
Muurlink, OT ORCiD: 0000-0002-8251-9521The endogenous and self-sustained circadian rhythm generated ...
A major consequence of the world industrialized lifestyle is the increasing period of unnatural ligh...
A major consequence of the world industrialized lifestyle is the increasing period of unnatural ligh...
Objective To examine whether sleep traits have a causal effect on risk of breast cancer. Design Men...
Clock genes are expressed in a self-perpetuating, circadian pattern in virtually every tissue includ...
Background: Disruption of sleep patterns, and thereby the internal body clock, of shift workers dir...
Background: Circadian disruption is hypothesized to impact reproductive signaling, which in turn has...
Circadian disruption has been linked with inflammation, an established cancer risk factor. Per3 cloc...
Introduction: Circadian disruption has been linked to carcinogenesis in animal models and to breast ...
Circadian clocks are fundamental, time-tracking systems that allow organisms to adapt to the appropr...