A series of beta-aminoxypropionic acids (AOPAs) had previously been designed and synthesised as analogues of antiinflammatory arylacetic acids (ArAAs) in which the Ar portion is substituted by the (methyleneaminoxy) methyl moiety (C = NOCH2, MAOMM). Most of these AOPAs had exhibited a significant antiinflammatory and antiaggregating activity. This paper reports the synthesis of a new series of beta-aminoxypropionic acids (SAOPAs) which include the saturated (methylaminoxy)methyl moiety (CHNH-OCH2, SMAOMM) in the place of the MAOMM present in AOPAs. The antiinflammatory activity of SAOPAs was evaluated by the carrageenan-induced paw edema method and the antiaggregating activity was evaluated by means of tests using arachidonic acid (AA) and ...
A series of anilides and phenyl esters of piperidine-3-carboxylic acid (nipecotic acid) were synthes...
Actual and postulated roles of glycerophospholipids in a number of biological systems, processes, an...
The article describes a two-step synthesis of diastereomeric 3-hydroxy-2methyl-3-( 4-biphenylyl) but...
A series of beta-aminoxypropionic acids (AOPAs) had previously been designed and synthesised as anal...
This paper reports the platelet anti-aggregating activity induced by arachidonic acid (AA) and by ad...
This paper reports the platelet anti-aggregating activity induced by arachidonic acid (AA) and by ad...
Previous experimental and theoretical studies carried out on the mechanism of action of adrenergic d...
An examination of the antiinflammatory properties of certain β-aminoxypropionic acids A (AOPAs) prev...
Department of Chemistry, University of Jammu, Jammu-180 004 Manuscript received 12 September 1994, ...
Some optically active 3-(arylmethylidene)aminoxy- (3a-g, 4a-g) and fluorenylideneaminoxy-2-methylpro...
The arachidonic acid is a precursor in the synthesis of eicosanoids: through the action of cyclooxyg...
The synthesis of some N,N-disubstituted 4-amino-5,6,7,8-tetrahydro-3,6- diphenyl-2H-1-benzopyran-2-o...
The paper presents the synthesis of benzimidazole derivatives starting from asparagic acid. The reac...
Background: Nonsteriodal anti-inflammatory drugs (NSAIDs) are numerous and widely used for more than...
Previous work in this laboratory demonstrated that a series of benzoic acid analogs, with only minor...
A series of anilides and phenyl esters of piperidine-3-carboxylic acid (nipecotic acid) were synthes...
Actual and postulated roles of glycerophospholipids in a number of biological systems, processes, an...
The article describes a two-step synthesis of diastereomeric 3-hydroxy-2methyl-3-( 4-biphenylyl) but...
A series of beta-aminoxypropionic acids (AOPAs) had previously been designed and synthesised as anal...
This paper reports the platelet anti-aggregating activity induced by arachidonic acid (AA) and by ad...
This paper reports the platelet anti-aggregating activity induced by arachidonic acid (AA) and by ad...
Previous experimental and theoretical studies carried out on the mechanism of action of adrenergic d...
An examination of the antiinflammatory properties of certain β-aminoxypropionic acids A (AOPAs) prev...
Department of Chemistry, University of Jammu, Jammu-180 004 Manuscript received 12 September 1994, ...
Some optically active 3-(arylmethylidene)aminoxy- (3a-g, 4a-g) and fluorenylideneaminoxy-2-methylpro...
The arachidonic acid is a precursor in the synthesis of eicosanoids: through the action of cyclooxyg...
The synthesis of some N,N-disubstituted 4-amino-5,6,7,8-tetrahydro-3,6- diphenyl-2H-1-benzopyran-2-o...
The paper presents the synthesis of benzimidazole derivatives starting from asparagic acid. The reac...
Background: Nonsteriodal anti-inflammatory drugs (NSAIDs) are numerous and widely used for more than...
Previous work in this laboratory demonstrated that a series of benzoic acid analogs, with only minor...
A series of anilides and phenyl esters of piperidine-3-carboxylic acid (nipecotic acid) were synthes...
Actual and postulated roles of glycerophospholipids in a number of biological systems, processes, an...
The article describes a two-step synthesis of diastereomeric 3-hydroxy-2methyl-3-( 4-biphenylyl) but...