Purpose: To present the latest quality assurance and characterization tests of the RADPOS 4‐D in vivo dosimetry system. Method and Materials: The dosimetric evaluation of this system included the measurement of in‐air dose profiles in [formula omitted], 6 MV, and 18 MV beams, and the investigation of the dependence of detector response on beam angle and field size. The stability and accuracy of the positioning component of the RADPOS detector was studied as well as the effect of metals and other commonly used materials on the RADPOS signal. Results: The dose profiles measured with the RADPOS detector and the diode agreed in within 0.41%, 0.53%, and 2.69% for the [formula omitted], 6 MV, and 18 MV beams, respectively. The angular response of...