Add to ORKGThese data reveal a dominant immunosuppressive function of B cell-derived IL-10 in the Lyn-deficient model of autoimmunity, extending our current understanding of the role of IL-10 and IL-10-producing B cells in SL
Autoimmunity is traditionally attributed to altered lymphoid cell selection and/or tolerance, wherea...
To establish strategies for immunotherapy of B-cell lymphoma, it is mandatory to gain deeper insight...
IL-10 is an important anti-inflammatory cytokine that plays important roles in controlling inflammat...
Lyn kinase deficient mice represent a well established genetic model of autoimmune/autoinflammatory ...
AbstractThe Src family protein-tyrosine kinase Lyn associates physically with the BCR and has been s...
IL-10 plays a central role in restraining the vigor of inflammatory responses, but the critical cell...
AbstractMice homozygous for a disruption at the Lyn locus display abnormalities associated with the ...
AbstractLyn-deficient mice were generated to analyze the role of Lyn in B cell antigen receptor (BCR...
The Lyn tyrosine kinase regulates inhibitory signaling in B and myeloid cells: loss of Lyn results i...
© 2011 Dr. Evelyn TsantikosThis thesis dissects the nature of autoimmune disease development in mice...
Systemic lupus erythematosus (SLE) is a highly heterogeneous autoimmune disease characterised by the...
Mice homozygous for a disruption at the Lyn locus display abnormalities associated with the B lympho...
Interleukin-10 (IL-10) is known to be a tolerogenic cytokine since it inhibits pro-inflammatory cyto...
SummaryB cells can suppress autoimmunity by secreting interleukin-10 (IL-10). Although subpopulation...
ABSTRACT. The B lymphocyte compartment is comprised of B-1 and B-2 cells. The former is divided into...
Autoimmunity is traditionally attributed to altered lymphoid cell selection and/or tolerance, wherea...
To establish strategies for immunotherapy of B-cell lymphoma, it is mandatory to gain deeper insight...
IL-10 is an important anti-inflammatory cytokine that plays important roles in controlling inflammat...
Lyn kinase deficient mice represent a well established genetic model of autoimmune/autoinflammatory ...
AbstractThe Src family protein-tyrosine kinase Lyn associates physically with the BCR and has been s...
IL-10 plays a central role in restraining the vigor of inflammatory responses, but the critical cell...
AbstractMice homozygous for a disruption at the Lyn locus display abnormalities associated with the ...
AbstractLyn-deficient mice were generated to analyze the role of Lyn in B cell antigen receptor (BCR...
The Lyn tyrosine kinase regulates inhibitory signaling in B and myeloid cells: loss of Lyn results i...
© 2011 Dr. Evelyn TsantikosThis thesis dissects the nature of autoimmune disease development in mice...
Systemic lupus erythematosus (SLE) is a highly heterogeneous autoimmune disease characterised by the...
Mice homozygous for a disruption at the Lyn locus display abnormalities associated with the B lympho...
Interleukin-10 (IL-10) is known to be a tolerogenic cytokine since it inhibits pro-inflammatory cyto...
SummaryB cells can suppress autoimmunity by secreting interleukin-10 (IL-10). Although subpopulation...
ABSTRACT. The B lymphocyte compartment is comprised of B-1 and B-2 cells. The former is divided into...
Autoimmunity is traditionally attributed to altered lymphoid cell selection and/or tolerance, wherea...
To establish strategies for immunotherapy of B-cell lymphoma, it is mandatory to gain deeper insight...
IL-10 is an important anti-inflammatory cytokine that plays important roles in controlling inflammat...