We here present data on immune gene expression of chemokines, chemokine receptors, cytokines and regulatory T-cell (T-reg) markers in chronic patients suffering from either schizophrenia (SCZ, N=20) or bipolar disorder (BD=20) compared with healthy controls (HCs, N=20). We extracted RNA from peripheral blood mononuclear cells and performed real-time (RT)-PCR to measure mRNA levels of chemokines, chemokine receptors, cytokines and T-reg markers. All the analyses were Bonferroni-corrected. The classical monocyte activation (M1) markers il6, ccl3 were significantly increased in BD as compared with both HC and SCZ patients (P=0.03 and P=0.002; P=0.024 and P=0.021, respectively), whereas markers of alternative (M2) monocyte activation ccl1, ccl2...
We recently described a pro-inflammatory gene expression signature in the monocytes of 60% of patien...
Aim To investigate whether circulating T cells including regulatory T cells (Treg) and derived cytok...
Objectives: We recently described a monocyte pro-inflammatory state in patients with bipolar disorde...
We here present data on immune gene expression of chemokines, chemokine receptors, cytokines and reg...
Accumulating evidence indicates an activated inflammatory response system as a vulnerability factor ...
ObjectivesExisting and previously published datasets were examined for associations between illness ...
This review describes patients with schizophrenia and bipolar disorder. In such patients, a high inf...
There is now evidence that, based on cytokine profiles, bipolar disorder (BD) is accompanied by simu...
Several lines of evidence point to the key role of neurobiological mechanisms and shared genetic bac...
BACKGROUND:Over the past 30 years, evidence has been accumulating for an immunological componen...
Abstract Background Over the past 30 years, evidence has been accumulating for an immunological comp...
Background: Previously, we found an increased prevalence of thyroid autoantibodies in patients with ...
We recently described a pro-inflammatory gene expression signature in the monocytes of 60% of patien...
Aim To investigate whether circulating T cells including regulatory T cells (Treg) and derived cytok...
Objectives: We recently described a monocyte pro-inflammatory state in patients with bipolar disorde...
We here present data on immune gene expression of chemokines, chemokine receptors, cytokines and reg...
Accumulating evidence indicates an activated inflammatory response system as a vulnerability factor ...
ObjectivesExisting and previously published datasets were examined for associations between illness ...
This review describes patients with schizophrenia and bipolar disorder. In such patients, a high inf...
There is now evidence that, based on cytokine profiles, bipolar disorder (BD) is accompanied by simu...
Several lines of evidence point to the key role of neurobiological mechanisms and shared genetic bac...
BACKGROUND:Over the past 30 years, evidence has been accumulating for an immunological componen...
Abstract Background Over the past 30 years, evidence has been accumulating for an immunological comp...
Background: Previously, we found an increased prevalence of thyroid autoantibodies in patients with ...
We recently described a pro-inflammatory gene expression signature in the monocytes of 60% of patien...
Aim To investigate whether circulating T cells including regulatory T cells (Treg) and derived cytok...
Objectives: We recently described a monocyte pro-inflammatory state in patients with bipolar disorde...