Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis
- G. Bonnier
- A. Roche
- D. Romascano
- S. Simioni
- D. Meskaldji
- D. Rotzinger
- A. Lin
- M. Schluep
- R. Du Pasquier
- T. Sumpf
- J. Frahm
- J. P. Thiran
- G. Krueger
- C. Granziera
- MENEGAZ, Gloria
DOIAbstract
Introduction: In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques to study brain microstructural alterations in earlyrelapsing-remitting MS (RRMS) patients with minor deficits. Further, we investigated the potential use of advanced MRI to predict functional performances in these patients
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