Add to ORKGAging and chronic alcohol consumption affects DNA methylation, changing gene transcription. It is not yet known whether these factors also alter DNA hydroxymethylation (hmC), an epigenetic mark produced by oxidation of methylcytosine.This is the first study demonstrating the effects of chronic alcohol consumption and aging on DNA hmC levels. Chronic alcohol consumption differently affects DNA hmC in young and old mice
Alcohol use disorder (AUD) is a highly prevalent and pernicious substance use disorder that is chara...
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigen...
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigen...
BACKGROUND:Aging and chronic alcohol consumption are both modifiers of DNA methylation, but it is no...
Global DNA hydroxymethylation is markedly decreased in human cancers, including hepatocellular carci...
Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chronic disea...
Abstract Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chro...
Aging is associated with changes in global DNA methylation (mC), but changes in DNA hydroxymethylati...
BACKGROUND: Aging is one of the most important risk factors for cancer. It appears that aberrant ep...
Genetic, epigenetic, and environmental factors influence the development of alcohol dependence (AD)....
DNA methylation may be one of the mechanisms by which alcohol consumption is associated with the ris...
DNA methylation may be one of the mechanisms by which alcohol consumption is associated with the ris...
Chronic alcohol abuse and dependence are associated with dysfunctional dopaminergic neurotransmissio...
Methylation at C-5 (5-mdC) of CpG base pairs, the most abundant epigenetic modification of DNA, is c...
<p>DNA methylation at cytosine-phosphate-guanine (CpG) dinucleotides changes as a function of age in...
Alcohol use disorder (AUD) is a highly prevalent and pernicious substance use disorder that is chara...
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigen...
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigen...
BACKGROUND:Aging and chronic alcohol consumption are both modifiers of DNA methylation, but it is no...
Global DNA hydroxymethylation is markedly decreased in human cancers, including hepatocellular carci...
Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chronic disea...
Abstract Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chro...
Aging is associated with changes in global DNA methylation (mC), but changes in DNA hydroxymethylati...
BACKGROUND: Aging is one of the most important risk factors for cancer. It appears that aberrant ep...
Genetic, epigenetic, and environmental factors influence the development of alcohol dependence (AD)....
DNA methylation may be one of the mechanisms by which alcohol consumption is associated with the ris...
DNA methylation may be one of the mechanisms by which alcohol consumption is associated with the ris...
Chronic alcohol abuse and dependence are associated with dysfunctional dopaminergic neurotransmissio...
Methylation at C-5 (5-mdC) of CpG base pairs, the most abundant epigenetic modification of DNA, is c...
<p>DNA methylation at cytosine-phosphate-guanine (CpG) dinucleotides changes as a function of age in...
Alcohol use disorder (AUD) is a highly prevalent and pernicious substance use disorder that is chara...
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigen...
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigen...