No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age.

We investigated the association between 9 polymorphisms of genes encoding hemostasis factors and myocardial infarction in a large sample of young patients chosen because they have less coronary atherosclerosis than older patients, and thus their disease is more likely to be related to a genetic predisposition to a prothrombotic state.This nationwide case-control study involved 1210 patients who had survived a first myocardial infarction at an age of