Influence of haemodialysis on lipoprotein(a), high sensitivity-C Reactive Protein, apolipoprotein A and B.

Objectives: There is debate on the influence of haemodialysis (HD) on lipoprotein(a). Design and methods: Lp(a), apo A, apo B and high-sensitivity C-reactive protein (hs-CRP) were measured in 46 patients pre- and post-HD. Results: The median Lp(a) concentration significantly decreased post-HD (106 vs. 145 mg/L, p < 0.001). No significant variations were observed for apo A, apo B and hs-CRP. Comparable results were observed with high- and low-flux membranes. Conclusion: HD is effective in lowering Lp(a). © 2007 The Canadian Society of Clinical Chemists