Celiac Disease: Its Neuropsychiatric Manifestations and Its Relevance to the Practicing Pediatrician

Our understanding of celiac disease has evolved considerably in the past several years. Once recognized as a gastrointestinal disease of children, celiac disease is now understood to have many extraintestinal symptoms inclusive of various neuropsychiatric manifestations. The aim of this article is to review our current understanding of celiac disease and explore the possible mechanisms of pathogenesis which may lead to these neuropsychiatric symptoms. Relevance to the practicing pediatrician is also addressed