Man has always been curious about his own mind--how and why it works. The essentials of its function must eventually be pushed back to the cellular level. Thus, it is on the neuron that the structural and functional integrity of the nervous system largely rests. In this project, through histology of the human brain, I have investigated one aspect of the neuron: that of the differential accumulation of lipofuscin, the old age pigment
grantor: University of TorontoMagnitude, rate and distribution pattern of lipofuscin accum...
Lipofuscin accumulation is a characteristic feature of senescent postmitotic neuronal cells but estr...
This project aimed to explore factors that modulate neurolipofuscin accumulation, using two experime...
Despite aging being by far the greatest risk factor for highly prevalent neurodegenerative disorders...
The extent of deposition of lipofuscin (lipochrome, yellow pigment, wear and tear pigment, ceroid) i...
Lipofuscin pigment accumulation is among the most prominent markers of cellular aging in postmitotic...
Lipofuscin pigment accumulation is among the most prominent markers of cellular aging in postmitotic...
Increased oxidative stress has been associated with several neurodegenerative diseases such as Alzhe...
The extent of deposition of lipofuscin in 66 nuclei of the aged human brain was classified systemati...
Lipofuscin pigment formation and distribution in the Mes. N.5 neurons, trigeminal and spinal ganglia...
By using fluorescence microscopy and microfluorimetric techniques, the effects of ageing and of 11 m...
Increased oxidative stress has been associated with several neurodegenerative diseases such as Alzhe...
The primary culprit responsible for Alzheimer’s disease (AD) remains unknown. Aβ protein has been id...
The formation of autofluorescent lipopigment or lipofuscin is a highly consistent and reliable cytol...
Item does not contain fulltextLipofuscin accumulation is a characteristic feature of senescent postm...
grantor: University of TorontoMagnitude, rate and distribution pattern of lipofuscin accum...
Lipofuscin accumulation is a characteristic feature of senescent postmitotic neuronal cells but estr...
This project aimed to explore factors that modulate neurolipofuscin accumulation, using two experime...
Despite aging being by far the greatest risk factor for highly prevalent neurodegenerative disorders...
The extent of deposition of lipofuscin (lipochrome, yellow pigment, wear and tear pigment, ceroid) i...
Lipofuscin pigment accumulation is among the most prominent markers of cellular aging in postmitotic...
Lipofuscin pigment accumulation is among the most prominent markers of cellular aging in postmitotic...
Increased oxidative stress has been associated with several neurodegenerative diseases such as Alzhe...
The extent of deposition of lipofuscin in 66 nuclei of the aged human brain was classified systemati...
Lipofuscin pigment formation and distribution in the Mes. N.5 neurons, trigeminal and spinal ganglia...
By using fluorescence microscopy and microfluorimetric techniques, the effects of ageing and of 11 m...
Increased oxidative stress has been associated with several neurodegenerative diseases such as Alzhe...
The primary culprit responsible for Alzheimer’s disease (AD) remains unknown. Aβ protein has been id...
The formation of autofluorescent lipopigment or lipofuscin is a highly consistent and reliable cytol...
Item does not contain fulltextLipofuscin accumulation is a characteristic feature of senescent postm...
grantor: University of TorontoMagnitude, rate and distribution pattern of lipofuscin accum...
Lipofuscin accumulation is a characteristic feature of senescent postmitotic neuronal cells but estr...
This project aimed to explore factors that modulate neurolipofuscin accumulation, using two experime...