Effect of Essential Oil Cinnnamomum Zylanicum on Biofilm Producing MDR Clinical Isolates of Pseudomonas Aeruginosa

Pseudomonas aeruginosa is an opportunistic pathogenic bacterium associated with various infections. Along with its resistance to drugs, the biofilm forming strategy has drastically reduced effectiveness of antipseuodomal drugs as well as reduced provoking appropriate immune response. Biofilm are extracellular polymeric substances (EPS) that hold microbial cells together to a surface. This present condition focuses on remedial source to treat this very notorious multi drug resistant (MDR) biofilm producing strain of P. aeruginosa. Quorum sensing (QS) is chemical signalling mechanism controlling virulence factor with biofilm formation ability. Biofilm formed by the population of bacteria act as a protective environment. Bacteria sustaining in biofilms demonstrate distinct features like different physiology and immense resistance to immune system and antibiotics, biofilm act a source of chronic and persistent infections. Various diseases are associated with the biofilm forming property of ubiquitous microorganism. It is essential to implement a better parameter for antibiotics resistant strains. Solving this problem present study aims at biofilm inhibitory activity of nbspCinnnamomum zylanicum.As biofilm act as major factor for drug resistance, essential oils potentially inhibit biofilm producing MDR strains. The Cinnnamomum zylanicum oil had strong inhibitory activity against multidrug resistant strains and its biofilm inhibiting activity contribute over it