Our objectives are to determine the molecular mechanism of the incision step of excision repair of ultraviolet (UV) light damaged DNA in eukaryotic organisms, using the yeast Saccharomyces cerevisiae as a model system, and to study the human homologs of yeast excision repair and postreplication repair proteins progress is described
textabstractAn intricate network of repair systems safeguards the integrity of genetic material, by ...
A newly characterized radl missense mutation (radl-20) in the yeast Saccharomyces cerevisiae maps to...
The human excision repair gene ERCC-7 was cloned after DNA mediated gene transfer to the CHO mutant ...
grantor: University of TorontoThe integrity of the genetic material is constantly threaten...
Knowledge about the DNA excision repair system is increasing rapidly. A detailed model for this proc...
The removal of UV radiation-induced pyrimidine dimers and (6–4) photoproducts as well as other bulky...
AbstractUsing a DNA-protein binding assay, we have previously identified and characterized a UV-dama...
The genetic disease xeroderma pigmentosum (XP) demonstrates the association between defective repair...
In human cells DNA damage caused by UV light is mainly repaired by the nucleotide excision repair pa...
DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damage, which...
<div><p>DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damag...
Schizosaccharomyces pombe cells deficient in nucleo-tide excision repair (NER) are still able to rem...
International audienceExcision repair defects of Saccharomyces cerevisiae rad1-1, rad4-4, rad7-1 and...
The work presented in this thesis aims to contribute to understanding of the molecular mechanisms th...
Recent years have witnessed remarkable progress in the investigative field that embraces how living ...
textabstractAn intricate network of repair systems safeguards the integrity of genetic material, by ...
A newly characterized radl missense mutation (radl-20) in the yeast Saccharomyces cerevisiae maps to...
The human excision repair gene ERCC-7 was cloned after DNA mediated gene transfer to the CHO mutant ...
grantor: University of TorontoThe integrity of the genetic material is constantly threaten...
Knowledge about the DNA excision repair system is increasing rapidly. A detailed model for this proc...
The removal of UV radiation-induced pyrimidine dimers and (6–4) photoproducts as well as other bulky...
AbstractUsing a DNA-protein binding assay, we have previously identified and characterized a UV-dama...
The genetic disease xeroderma pigmentosum (XP) demonstrates the association between defective repair...
In human cells DNA damage caused by UV light is mainly repaired by the nucleotide excision repair pa...
DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damage, which...
<div><p>DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damag...
Schizosaccharomyces pombe cells deficient in nucleo-tide excision repair (NER) are still able to rem...
International audienceExcision repair defects of Saccharomyces cerevisiae rad1-1, rad4-4, rad7-1 and...
The work presented in this thesis aims to contribute to understanding of the molecular mechanisms th...
Recent years have witnessed remarkable progress in the investigative field that embraces how living ...
textabstractAn intricate network of repair systems safeguards the integrity of genetic material, by ...
A newly characterized radl missense mutation (radl-20) in the yeast Saccharomyces cerevisiae maps to...
The human excision repair gene ERCC-7 was cloned after DNA mediated gene transfer to the CHO mutant ...