Background/Aims: Compounds of Cannabis sativa are known to exert anti-inflammatory properties, some of them without inducing psychotropic side effects. Cannabidiol (CBD) is such a side effect-free phytocannabinoid that improves chemically induced colitis in rodents when given intraperitoneally. Here, we tested the possibility whether rectal and oral application of CBD would also ameliorate colonic inflammation, as these routes of application may represent a more appropriate way for delivering drugs in human colitis. Methods: Colitis was induced in CD1 mice by trinitrobenzene sulfonic acid. Individual groups were either treated with CBD intraperitoneally (10 mg/kg), orally (20 mg/kg) or intrarectally (20 mg/kg). Colitis was evaluated by macr...
Cannabis sativa and its extracts have been used for centuries both medicinally and recreationally. T...
Original article can be found at : http://www3.interscience.wiley.com/ Copyright The British Pharmac...
Enteric glial cells (EGC) actively mediate acute and chronic inflammation in the gut; EGC proliferat...
Background/Aims: Compounds of Cannabis sativa are known to exert anti-inflammatory properties, some ...
Background: Non-psychotropic atypical cannabinoids have therapeutic potential in a variety of inflam...
Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel...
Inflammatory bowel disease affects millions of individuals; nevertheless, pharmacological treatment ...
Patients with ulcerative colitis (UC) using marijuana have been reported to experience symptomatic b...
ameliorating effect on colitis. Conclusion: The data of this study indicate that in addition to intr...
Background and Aims: In an attempt to further investigate the role of cannabinoid (CB) system in the...
Cannabis sativa and its extracts have been used for centuries both medicinally and recreationally. T...
Original article can be found at : http://www3.interscience.wiley.com/ Copyright The British Pharmac...
Enteric glial cells (EGC) actively mediate acute and chronic inflammation in the gut; EGC proliferat...
Background/Aims: Compounds of Cannabis sativa are known to exert anti-inflammatory properties, some ...
Background: Non-psychotropic atypical cannabinoids have therapeutic potential in a variety of inflam...
Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel...
Inflammatory bowel disease affects millions of individuals; nevertheless, pharmacological treatment ...
Patients with ulcerative colitis (UC) using marijuana have been reported to experience symptomatic b...
ameliorating effect on colitis. Conclusion: The data of this study indicate that in addition to intr...
Background and Aims: In an attempt to further investigate the role of cannabinoid (CB) system in the...
Cannabis sativa and its extracts have been used for centuries both medicinally and recreationally. T...
Original article can be found at : http://www3.interscience.wiley.com/ Copyright The British Pharmac...
Enteric glial cells (EGC) actively mediate acute and chronic inflammation in the gut; EGC proliferat...