The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to examine the possible interaction between pp89 and chromatin. pp89 expressed constitutively in cell line BALB/c 3T3 IE1 does not interact with condensed chromatin. As observed in infected cells, pp89 is localized within the nucleus of cells during interphase but spreads throughout the cell plasma following degradation of the nuclear membrane during early mitosis. In late telophase, pp89 is reorganized within the nucleus. Analysis of pp89 deletion mutants and of fragments generated by cleavage at ...
The 72-kDa immediate early 1 (IE1) protein encoded by human cytomegalovirus (hCMV) is a nuclearly lo...
To study trans-activation of gene expression by murine cytomegalovirus (MCMV) immediate-early (IE) p...
The immediate-early (IE) genes of murine cytomegalovirus (MCMV) are expressed in the absence of prio...
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA...
The product of the ie 1 gene, the regulatory immediate early protein pp89 of murine cytomegalovirus ...
The gene regulatory immediate arly protein, pp89, of murine cytomegalovirus interacts with both DNA-...
The conditions that permit the interaction of immediate-early proteins of murine cytornegalovirus (M...
The product of the iel gene, the regulatory immediate early protein pp89 of murine cytomegalovirus (...
In murine cytomegalovirus, abundant immediate-early transcription originates from 0.769 to 0.815 map...
The 72-kDa immediate early 1 (IE1) protein encoded by human cytomegalovirus (hCMV) is a nuclearly lo...
To study trans-activation of gene expression by murine cytomegalovirus (MCMV) immediate-early (IE) p...
The immediate-early (IE) genes of murine cytomegalovirus (MCMV) are expressed in the absence of prio...
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA...
The product of the ie 1 gene, the regulatory immediate early protein pp89 of murine cytomegalovirus ...
The gene regulatory immediate arly protein, pp89, of murine cytomegalovirus interacts with both DNA-...
The conditions that permit the interaction of immediate-early proteins of murine cytornegalovirus (M...
The product of the iel gene, the regulatory immediate early protein pp89 of murine cytomegalovirus (...
In murine cytomegalovirus, abundant immediate-early transcription originates from 0.769 to 0.815 map...
The 72-kDa immediate early 1 (IE1) protein encoded by human cytomegalovirus (hCMV) is a nuclearly lo...
To study trans-activation of gene expression by murine cytomegalovirus (MCMV) immediate-early (IE) p...
The immediate-early (IE) genes of murine cytomegalovirus (MCMV) are expressed in the absence of prio...