Add to ORKGHerein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two sets of conditions were developed for this transformation, allowing for the use of either aryl chlorides or bromides as electrophiles. Utilizing a highly electron‐rich, dialkylphosphine ligand, we have been able to construct α‐quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee)
Herein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two ...
Pyrrolidinone moieties with a tertiary stereogenic centre at the C-5 position are prevalent in a num...
The first regio-, diastereo-, and enantioselective allylic alkylation of acyclic β-ketoesters to for...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
We report the palladium-catalyzed asymmetric allylic alkylation of 1,4-diazepan-5-ones. This reactio...
The enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted α-h...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
Herein, we report a Cu‐catalyzed enantioselective allylic alkylation using a γ‐butyrolactone‐derived...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
Herein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two ...
Pyrrolidinone moieties with a tertiary stereogenic centre at the C-5 position are prevalent in a num...
The first regio-, diastereo-, and enantioselective allylic alkylation of acyclic β-ketoesters to for...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
We report the palladium-catalyzed asymmetric allylic alkylation of 1,4-diazepan-5-ones. This reactio...
The enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted α-h...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
Herein, we report a Cu‐catalyzed enantioselective allylic alkylation using a γ‐butyrolactone‐derived...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
Herein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two ...
Pyrrolidinone moieties with a tertiary stereogenic centre at the C-5 position are prevalent in a num...
The first regio-, diastereo-, and enantioselective allylic alkylation of acyclic β-ketoesters to for...