Add to ORKGThe first direct enantioselective catalytic α-oxidation of carbonyls has been accomplished. The use of enamine catalysis has provided a new organocatalytic strategy for the enantioselective oxyamination of aldehydes, to generate α-oxyaldehydes, important chiral synthons for natural product and medicinal agent synthesis. The use of l-proline as the asymmetric catalyst has been found to mediate the oxidation of a large variety of aldehyde substrates with nitrosobenzene serving as the electrophilic oxidant. A diverse spectrum of aldehyde substrates can also be accommodated in this new organocatalytic transformation. While catalyst quantities of 2 mol % were generally employed in this study, successful oxidations conducted using catalyst loadin...
The asymmetric α-addition of relatively nonpolar hydrocarbon substrates, such as allyl and aryl grou...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
The first direct enantioselective catalytic α-oxidation of carbonyls has been accomplished. The use ...
The first direct enantioselective catalytic α-chlorination of aldehydes has been accomplished. The u...
The first direct enantioselective catalytic α-chlorination of aldehydes has been accomplished. The u...
The first enantioselective organocatalytic α-enolation of aldehydes has been accomplished using sing...
The first enantioselective organocatalytic α-enolation of aldehydes has been accomplished using sing...
The first enantioselective organocatalytic α-enolation of aldehydes has been accomplished using sing...
The first direct enantioselective catalytic α-fluorination of aldehydes has been accomplished. The u...
The first direct enantioselective catalytic α-fluorination of aldehydes has been accomplished. The u...
The first enantioselective organocatalytic alkylation of electron-rich benzene rings with α,β-unsatu...
The first enantioselective organocatalytic alkylation of electron-rich benzene rings with α,β-unsatu...
The first enantioselective organocatalytic Mukaiyama−Michael reaction using α,β-unsaturated aldehyde...
The asymmetric α-addition of relatively nonpolar hydrocarbon substrates, such as allyl and aryl grou...
The asymmetric α-addition of relatively nonpolar hydrocarbon substrates, such as allyl and aryl grou...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
The first direct enantioselective catalytic α-oxidation of carbonyls has been accomplished. The use ...
The first direct enantioselective catalytic α-chlorination of aldehydes has been accomplished. The u...
The first direct enantioselective catalytic α-chlorination of aldehydes has been accomplished. The u...
The first enantioselective organocatalytic α-enolation of aldehydes has been accomplished using sing...
The first enantioselective organocatalytic α-enolation of aldehydes has been accomplished using sing...
The first enantioselective organocatalytic α-enolation of aldehydes has been accomplished using sing...
The first direct enantioselective catalytic α-fluorination of aldehydes has been accomplished. The u...
The first direct enantioselective catalytic α-fluorination of aldehydes has been accomplished. The u...
The first enantioselective organocatalytic alkylation of electron-rich benzene rings with α,β-unsatu...
The first enantioselective organocatalytic alkylation of electron-rich benzene rings with α,β-unsatu...
The first enantioselective organocatalytic Mukaiyama−Michael reaction using α,β-unsaturated aldehyde...
The asymmetric α-addition of relatively nonpolar hydrocarbon substrates, such as allyl and aryl grou...
The asymmetric α-addition of relatively nonpolar hydrocarbon substrates, such as allyl and aryl grou...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...
Our laboratory has been engaged in the design of broadly useful new strategies for enantioselective ...