Add to ORKGUnderstanding the factors that determine molecular shape enables scientists to begin to understand and tailor molecular properties and reactivity. Many biomolecules and bioactive compounds contain aliphatic heterocyclic rings whose conformations play a major role in their biological activity. The interplay of a number of factors, both steric and electronic, is examined for 5-hydroxyhexahydropyrimidine (1) and related compounds with use of spectroscopy and molecular modeling
Molecular conformation plays an important role in many aspects of chemistry and at all scales. Study...
Molecular dynamics (MD) simulations play nowadays an increasingly important role in many areas of bi...
The conformational properties of daunomycin (1) and several analogues (2)\u2013(16) have been invest...
Understanding the factors that determine molecular shape enables scientists to begin to understand a...
Understanding the factors that determine molecular shape enables scientists to begin to understand a...
Some N.M.R. techniques used in conformational analysis, the principal factors peculiar to heterocycl...
Overall conformations of both anomeric per-O-acetylated glucosyl derivatives of 2,2,5,7,8-pentamethy...
Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor that causes growth arrest ...
Three small cluster oligosaccharide mimetics were synthesized, and their CDCl3 solution conformation...
The main focus of this thesis is on the ring conformations of carbohydrate molecules; how the confor...
The authors would like to acknowledge the EPSRC for funding.Determining the conformational preferenc...
1. It is shown by dipole-moment measurements and IR and PMR spectroscopy that 2-R-5,6-dichloro-1, 3-...
The endogenous cannabinoid anandamide (N-arachidonoylethanolamide) has been shown to possess higher...
Background: The advent of combinatorial chemistry has revived the interest in five-membered heterocy...
The first part of the thesis shows how nuclear magnetic resonance can he used to determine the energ...
Molecular conformation plays an important role in many aspects of chemistry and at all scales. Study...
Molecular dynamics (MD) simulations play nowadays an increasingly important role in many areas of bi...
The conformational properties of daunomycin (1) and several analogues (2)\u2013(16) have been invest...
Understanding the factors that determine molecular shape enables scientists to begin to understand a...
Understanding the factors that determine molecular shape enables scientists to begin to understand a...
Some N.M.R. techniques used in conformational analysis, the principal factors peculiar to heterocycl...
Overall conformations of both anomeric per-O-acetylated glucosyl derivatives of 2,2,5,7,8-pentamethy...
Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor that causes growth arrest ...
Three small cluster oligosaccharide mimetics were synthesized, and their CDCl3 solution conformation...
The main focus of this thesis is on the ring conformations of carbohydrate molecules; how the confor...
The authors would like to acknowledge the EPSRC for funding.Determining the conformational preferenc...
1. It is shown by dipole-moment measurements and IR and PMR spectroscopy that 2-R-5,6-dichloro-1, 3-...
The endogenous cannabinoid anandamide (N-arachidonoylethanolamide) has been shown to possess higher...
Background: The advent of combinatorial chemistry has revived the interest in five-membered heterocy...
The first part of the thesis shows how nuclear magnetic resonance can he used to determine the energ...
Molecular conformation plays an important role in many aspects of chemistry and at all scales. Study...
Molecular dynamics (MD) simulations play nowadays an increasingly important role in many areas of bi...
The conformational properties of daunomycin (1) and several analogues (2)\u2013(16) have been invest...