SpP3A1 and SpP3A2 are DNA-binding proteins that interact specifically with the same target sites in the regulatory domains of the Strongylocentrotus purpuratus CyIIIa gene and also of several other known genes. In this work we used antibodies raised against recombinant P3A1 and P3A2 to quantitate these transcription factors in eggs and in the nuclear compartments of embryos of various stages. Both proteins are present in unfertilized eggs, and both enter the embryonic nuclei early in development, but only P3A2 remains present in nuclei at functional concentrations beyond the early gastrula stage. Combined with earlier measurements of P3A site binding at cleavage stages, these measurements show that P3A1 would be replaced by P3A2 at target s...
We have characterized a sea urchin gene, SpOct, that encodes a 78-kDa POU-domain protein related to ...
In this paper we present a structural and functional characterization of a new sea urchin embryo tra...
Coup-TF, an orphan member of the nuclear receptor super family, has a fundamental role in the develo...
SpP3A1 and SpP3A2 are DNA-binding proteins that interact specifically with the same target sites in ...
AbstractSpP3A1 and SpP3A2 are DNA-binding proteins that interact specifically with the same target s...
The prevalence of mRNAs coding for the sea urchin embryo regulatory factors P3A1 and P3A2 was measur...
Previous work demonstrated that a negative regulatory interaction mediated by factor(s) termed 'P3A'...
Nine different embryonic transcription factors interact at specific target sites in the cis-regulato...
This communication concerns a very highly conserved inverted repeat sequence element that serves as ...
Nine different transcription factors of the Strongylocentrotus purpuratus embryo, belonging to diver...
AbstractTo understand how the maternally determined animal-vegetal polarity of the sea urchin embryo...
The CyIIIa actin gene of Strongylocentrotus purpuratus is transcribed exclusively in the embryonic ...
Previous gene-transfer experiments have identified a 2500-nucleotide 5' domain of the CyIIIa cytoske...
The experimental approach presented here aims to understand the mechanisms by which differential gen...
To understand how a eukaryote achieves differential transcription of genes in precise spatial patter...
We have characterized a sea urchin gene, SpOct, that encodes a 78-kDa POU-domain protein related to ...
In this paper we present a structural and functional characterization of a new sea urchin embryo tra...
Coup-TF, an orphan member of the nuclear receptor super family, has a fundamental role in the develo...
SpP3A1 and SpP3A2 are DNA-binding proteins that interact specifically with the same target sites in ...
AbstractSpP3A1 and SpP3A2 are DNA-binding proteins that interact specifically with the same target s...
The prevalence of mRNAs coding for the sea urchin embryo regulatory factors P3A1 and P3A2 was measur...
Previous work demonstrated that a negative regulatory interaction mediated by factor(s) termed 'P3A'...
Nine different embryonic transcription factors interact at specific target sites in the cis-regulato...
This communication concerns a very highly conserved inverted repeat sequence element that serves as ...
Nine different transcription factors of the Strongylocentrotus purpuratus embryo, belonging to diver...
AbstractTo understand how the maternally determined animal-vegetal polarity of the sea urchin embryo...
The CyIIIa actin gene of Strongylocentrotus purpuratus is transcribed exclusively in the embryonic ...
Previous gene-transfer experiments have identified a 2500-nucleotide 5' domain of the CyIIIa cytoske...
The experimental approach presented here aims to understand the mechanisms by which differential gen...
To understand how a eukaryote achieves differential transcription of genes in precise spatial patter...
We have characterized a sea urchin gene, SpOct, that encodes a 78-kDa POU-domain protein related to ...
In this paper we present a structural and functional characterization of a new sea urchin embryo tra...
Coup-TF, an orphan member of the nuclear receptor super family, has a fundamental role in the develo...