The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substrate 2 at pH5.5 (k_(cal) = 0.904 h^(−1), K_M = 324 μM). Hapten 1 is a competitive inhibitor of the antibody-catalyzed reaction. These results are significant for the development of antibodies for the sequence-specific hydrolysis of oligosaccharides
This thesis describes the development and study of catalytic antibodies capable of peptide bond form...
The hydrolysis of N-p-toluoylindole and its 3-formyl derivative, at pH 8.0, are accelerated by a fac...
The coupling of haptens to carrier proteins is required for the generation of antihapten antibody re...
The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substr...
To maximize the probability of obtaining an antibody peptidase, an efficient assay for the hydrolysi...
A new amine-oxide hapten was employed as an antigen, producing seven monoclonal antibodies (mAbs) fr...
An enzyme-like polyclonal antibody with high catalytic activity was isolated and purified from the a...
We report the first example of a monoclonal antibody-catalysed hydrolysis of a β-lactam where the an...
A new approach for producing catalytic antiidiotypic antibody was developed. A monoclonal anti-idiot...
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.Vita.Includes biblio...
A kinetically homogeneous anti-phosphate catalytic antibody preparation was shown to catalyse the hy...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Abstract: Catalytic antibodies are relatively slow catalysts with turnover numbers some 106 less tha...
AbstractBackground: Small organic molecules coupled to a carrier protein elicit an antibody response...
This thesis describes the development and study of catalytic antibodies capable of peptide bond form...
The hydrolysis of N-p-toluoylindole and its 3-formyl derivative, at pH 8.0, are accelerated by a fac...
The coupling of haptens to carrier proteins is required for the generation of antihapten antibody re...
The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substr...
To maximize the probability of obtaining an antibody peptidase, an efficient assay for the hydrolysi...
A new amine-oxide hapten was employed as an antigen, producing seven monoclonal antibodies (mAbs) fr...
An enzyme-like polyclonal antibody with high catalytic activity was isolated and purified from the a...
We report the first example of a monoclonal antibody-catalysed hydrolysis of a β-lactam where the an...
A new approach for producing catalytic antiidiotypic antibody was developed. A monoclonal anti-idiot...
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.Vita.Includes biblio...
A kinetically homogeneous anti-phosphate catalytic antibody preparation was shown to catalyse the hy...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Abstract: Catalytic antibodies are relatively slow catalysts with turnover numbers some 106 less tha...
AbstractBackground: Small organic molecules coupled to a carrier protein elicit an antibody response...
This thesis describes the development and study of catalytic antibodies capable of peptide bond form...
The hydrolysis of N-p-toluoylindole and its 3-formyl derivative, at pH 8.0, are accelerated by a fac...
The coupling of haptens to carrier proteins is required for the generation of antihapten antibody re...