Add to ORKGWe tested the theory that reactive oxygen species cause aging. We augmented the natural antioxidant systems of Caenorhabditis elegans with small synthetic superoxide dismutase/catalase mimetics. Treatment of wild-type worms increased their mean life-span by a mean of 44 percent, and treatment of prematurely aging worms resulted in normalization of their life-span (a 67 percent increase). It appears that oxidative stress is a major determinant of life-span and that it can be counteracted by pharmacological intervention
Johnson and Wood constructed recombinant inbred strains of Caenorhabditis elegans with life spans ra...
The free radical theory of aging postulates that aging is caused by damage induced by oxidative stre...
The superoxide radical (O-2(-)) has long been considered a major cause of aging. O-2(-) in cytosolic...
We tested the theory that reactive oxygen species cause aging. We augmented the natural antioxidant ...
We tested the theory that reactive oxygen species cause aging. We augmented the natural antioxidant ...
Reactive oxygen species (ROS) are important factors mediating aging according to the free radical th...
Excessive generation of reactive oxygen species within cells results in oxidative stress. Furthermor...
Despite more than 50 years of investigations into the free radical theory, the direct role of oxidat...
AbstractThe superoxide free radical (O2•−) has been viewed as a likely major contributor to aging. I...
Recently the relationship between oxidative stress and aging has been brought into question. It has ...
Natural antioxidants have recently emerged as a highly exciting and significant topic in anti-aging ...
Abstract Reactive oxygen species (ROS) are important factors mediating aging according to the free r...
SummaryAlthough historically reactive oxygen species have been implicated as a potential cause of ag...
The oxidative stress theory of aging postulates that aging results from the accumulation of molecula...
AbstractThe nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model org...
Johnson and Wood constructed recombinant inbred strains of Caenorhabditis elegans with life spans ra...
The free radical theory of aging postulates that aging is caused by damage induced by oxidative stre...
The superoxide radical (O-2(-)) has long been considered a major cause of aging. O-2(-) in cytosolic...
We tested the theory that reactive oxygen species cause aging. We augmented the natural antioxidant ...
We tested the theory that reactive oxygen species cause aging. We augmented the natural antioxidant ...
Reactive oxygen species (ROS) are important factors mediating aging according to the free radical th...
Excessive generation of reactive oxygen species within cells results in oxidative stress. Furthermor...
Despite more than 50 years of investigations into the free radical theory, the direct role of oxidat...
AbstractThe superoxide free radical (O2•−) has been viewed as a likely major contributor to aging. I...
Recently the relationship between oxidative stress and aging has been brought into question. It has ...
Natural antioxidants have recently emerged as a highly exciting and significant topic in anti-aging ...
Abstract Reactive oxygen species (ROS) are important factors mediating aging according to the free r...
SummaryAlthough historically reactive oxygen species have been implicated as a potential cause of ag...
The oxidative stress theory of aging postulates that aging results from the accumulation of molecula...
AbstractThe nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model org...
Johnson and Wood constructed recombinant inbred strains of Caenorhabditis elegans with life spans ra...
The free radical theory of aging postulates that aging is caused by damage induced by oxidative stre...
The superoxide radical (O-2(-)) has long been considered a major cause of aging. O-2(-) in cytosolic...