Add to ORKGWe have synthesized and characterized a water-soluble gold(III) corrole (1-Au) that is highly toxic to cisplatin-resistant cancer cells. Relative to its 1-Ga analogue, axial ligands bind only weakly to 1-Au, which likely accounts for its lower affinity for human serum albumin (HSA). We suggest that the cytotoxicity of 1-Au may be related to this lower HSA affinity
Site-selective modifications of target proteins using specially designed small molecules is a powerf...
A novel gold(III) complex, [AuCl2{(S,S)-Et(2)eddl}]PF6, ((S,S)-Et(2)eddl = O,O-diethyl ester of ethy...
The discovery of cisplatin revolutionised the treatment of cancer and opened the door to investigati...
We have synthesized and characterized a water-soluble gold(III) corrole (1-Au) that is highly toxic ...
A gallium(III)-substituted amphiphilic corrole noncovalently associated with a targeting protein was...
Recent work has highlighted the potential of metallocorroles as versatile platforms for the developm...
The antiproliferative properties of a group of 13 structurally diverse gold(III) compounds, includin...
Corroles are exceptionally promising platforms for the development of agents for simultaneous cancer...
Gold(III) complexes have emerged as a versatile and effective class of metal‐based anticancer agents...
The molecular mechanisms of toxicity and cellular transport of anticancer metallodrugs, including pl...
Transition metals offer many possibilities in developing potent chemotherapeutic agents. They are en...
Corroles have been shown experimentally to cause cell cycle arrest, and there is some evidence that ...
We prepared four representative square planar gold(III) complexes - [AuCl3(Hpm)], [AuCl2(esal)], [Au...
Prompted by the successful clinical application of cisplatin in cancer therapy, worldwide efforts ha...
A series of novel ((CN)-N-boolean AND) cyclometallated Au(III) complexes of general formula [Au(py(b...
Site-selective modifications of target proteins using specially designed small molecules is a powerf...
A novel gold(III) complex, [AuCl2{(S,S)-Et(2)eddl}]PF6, ((S,S)-Et(2)eddl = O,O-diethyl ester of ethy...
The discovery of cisplatin revolutionised the treatment of cancer and opened the door to investigati...
We have synthesized and characterized a water-soluble gold(III) corrole (1-Au) that is highly toxic ...
A gallium(III)-substituted amphiphilic corrole noncovalently associated with a targeting protein was...
Recent work has highlighted the potential of metallocorroles as versatile platforms for the developm...
The antiproliferative properties of a group of 13 structurally diverse gold(III) compounds, includin...
Corroles are exceptionally promising platforms for the development of agents for simultaneous cancer...
Gold(III) complexes have emerged as a versatile and effective class of metal‐based anticancer agents...
The molecular mechanisms of toxicity and cellular transport of anticancer metallodrugs, including pl...
Transition metals offer many possibilities in developing potent chemotherapeutic agents. They are en...
Corroles have been shown experimentally to cause cell cycle arrest, and there is some evidence that ...
We prepared four representative square planar gold(III) complexes - [AuCl3(Hpm)], [AuCl2(esal)], [Au...
Prompted by the successful clinical application of cisplatin in cancer therapy, worldwide efforts ha...
A series of novel ((CN)-N-boolean AND) cyclometallated Au(III) complexes of general formula [Au(py(b...
Site-selective modifications of target proteins using specially designed small molecules is a powerf...
A novel gold(III) complex, [AuCl2{(S,S)-Et(2)eddl}]PF6, ((S,S)-Et(2)eddl = O,O-diethyl ester of ethy...
The discovery of cisplatin revolutionised the treatment of cancer and opened the door to investigati...