The tetracyclic core of the integrastatin natural products has been prepared in a convergent and rapidmanner. Our strategy relies upon a palladium(II)-catalyzed oxidative cyclization to form the central [3.3.1]-dioxabicycle of the natural product core. Overall, the core has been completed in only 4 linear steps from known compounds
A largely catalysis based approach to optically active haouamine A (−)-1 is presented, which provide...
The mild reaction conditions, remarkable functional group compatibility, and complete regioselectivi...
A concise route toward the syntheses of (−)-drupacine and (+)- and (−)-cephalotaxine has been develo...
A facile method for the simple synthesis of tetracyclic indoloisoxazolidine frameworks from Baylis-H...
A straightforward total synthesis of the cyclooctenoid sesquiterpene dactylol (1) and of 3a-epi-dact...
Treatment of alkenylstannanes with Cu(OAc)2/Et3N affords the corresponding enol esters or ketones un...
Treat me gently: For a selective synthesis of the unusually sensitive cyclophanic α-pyrone neurymeno...
The combination of catalytic amounts of [Pd(PPh3)4], copper thiophene-2-carboxylate (CuTC) and [Ph2P...
An enantiodivergent strategy for the total chemical synthesis of both (+)- and (−)-dragmacidin F beg...
Herein we report our recent progress toward the enantioselective total synthesis of the diterpenoid ...
A reaction cascade comprising a rhodium-catalyzed C−H activation, a subsequent hydrometalation of an...
Exposure of enynes containing a hydroxyl group at one of the propargylic positions to catalytic amou...
Supplementary material for: [https://doi.org/10.1016/j.tetlet.2013.02.068]Related to published versi...
A tandem anionic 5-exo-dig cyclization/Claisen rearrangement sequence was used to effect a facile, “...
The first enantioselective ruthenium olefin metathesis catalysts have been prepared, and high enanti...
A largely catalysis based approach to optically active haouamine A (−)-1 is presented, which provide...
The mild reaction conditions, remarkable functional group compatibility, and complete regioselectivi...
A concise route toward the syntheses of (−)-drupacine and (+)- and (−)-cephalotaxine has been develo...
A facile method for the simple synthesis of tetracyclic indoloisoxazolidine frameworks from Baylis-H...
A straightforward total synthesis of the cyclooctenoid sesquiterpene dactylol (1) and of 3a-epi-dact...
Treatment of alkenylstannanes with Cu(OAc)2/Et3N affords the corresponding enol esters or ketones un...
Treat me gently: For a selective synthesis of the unusually sensitive cyclophanic α-pyrone neurymeno...
The combination of catalytic amounts of [Pd(PPh3)4], copper thiophene-2-carboxylate (CuTC) and [Ph2P...
An enantiodivergent strategy for the total chemical synthesis of both (+)- and (−)-dragmacidin F beg...
Herein we report our recent progress toward the enantioselective total synthesis of the diterpenoid ...
A reaction cascade comprising a rhodium-catalyzed C−H activation, a subsequent hydrometalation of an...
Exposure of enynes containing a hydroxyl group at one of the propargylic positions to catalytic amou...
Supplementary material for: [https://doi.org/10.1016/j.tetlet.2013.02.068]Related to published versi...
A tandem anionic 5-exo-dig cyclization/Claisen rearrangement sequence was used to effect a facile, “...
The first enantioselective ruthenium olefin metathesis catalysts have been prepared, and high enanti...
A largely catalysis based approach to optically active haouamine A (−)-1 is presented, which provide...
The mild reaction conditions, remarkable functional group compatibility, and complete regioselectivi...
A concise route toward the syntheses of (−)-drupacine and (+)- and (−)-cephalotaxine has been develo...