Add to ORKGA convenient method is disclosed for the synthesis of both 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones from b-ketoesters using a one-pot aryne acyl-alkylation/condensation procedure. When performed in conjunction with a one-step method for the synthesis of the b-ketoester substrates, this method provides a new route to these polyaromatic structures in only two steps from commercially available carboxylic acid starting materials. The utility of this approach is demonstrated in the synthesis of the atropisomeric P,N-ligand, QUINAP
An easy entry to uncommon 2-propargylbenzaldehydes was developed. 2-propargylbenzaldehydes demonstra...
An insertion of arenes into both imides and anhydrides via reactive aryne intermediates is presented...
Bibliography: pages 248-257.The naphtho[2,3-c]pyran ring system occurs not infrequently in Nature as...
A convenient method is disclosed for the synthesis of both 3-hydroxyisoquinolines and 2-hydroxy-1,4-...
1,3-Dimethylbenzisochromene-5,10-quinone 14 is obtained in good yield when 2-(1′-hydroxyethyl)-3-pro...
Three cascade reactions that provide access to various heterocyclic skeletons from quinols were deve...
An efficient and mild acyl-alkylation of arynes is described. The method is used to synthesize mediu...
The cascade radical cyclization of the benzannulated enyne-allenes provides an efficient synthetic p...
The last decade has seen an outgrowth in the development of synthetic methodologies exploiting benzy...
A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has b...
Irradiation of substituted 2-benzylidenecyclopentanone O-alkyl and O-acetyloximes in methanol provid...
textA general and efficient methodology for the synthesis of cis-2-substituted-1,2-dihydro-1-naphtho...
The synthesis of dihydroxy ketones such as 1 is usually accomplished by a sequence involving Friedel...
The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarbo...
Naphthoquinones are organic compounds naturally found in plants that have multiple medical benefits...
An easy entry to uncommon 2-propargylbenzaldehydes was developed. 2-propargylbenzaldehydes demonstra...
An insertion of arenes into both imides and anhydrides via reactive aryne intermediates is presented...
Bibliography: pages 248-257.The naphtho[2,3-c]pyran ring system occurs not infrequently in Nature as...
A convenient method is disclosed for the synthesis of both 3-hydroxyisoquinolines and 2-hydroxy-1,4-...
1,3-Dimethylbenzisochromene-5,10-quinone 14 is obtained in good yield when 2-(1′-hydroxyethyl)-3-pro...
Three cascade reactions that provide access to various heterocyclic skeletons from quinols were deve...
An efficient and mild acyl-alkylation of arynes is described. The method is used to synthesize mediu...
The cascade radical cyclization of the benzannulated enyne-allenes provides an efficient synthetic p...
The last decade has seen an outgrowth in the development of synthetic methodologies exploiting benzy...
A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has b...
Irradiation of substituted 2-benzylidenecyclopentanone O-alkyl and O-acetyloximes in methanol provid...
textA general and efficient methodology for the synthesis of cis-2-substituted-1,2-dihydro-1-naphtho...
The synthesis of dihydroxy ketones such as 1 is usually accomplished by a sequence involving Friedel...
The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarbo...
Naphthoquinones are organic compounds naturally found in plants that have multiple medical benefits...
An easy entry to uncommon 2-propargylbenzaldehydes was developed. 2-propargylbenzaldehydes demonstra...
An insertion of arenes into both imides and anhydrides via reactive aryne intermediates is presented...
Bibliography: pages 248-257.The naphtho[2,3-c]pyran ring system occurs not infrequently in Nature as...