This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed separation column, and an ESI nozzle. We also present the successful on-chip separation of protein digests by reverse phase (RP)-LC coupled with on-line mass spectrometer (MS) analysis
A microfabricated device has been developed in which electrospray ionization is performed directly f...
Seminal bioanalytical technologies for high-throughput analysis, such as flow cytometry and capillar...
Changes in liquid composition during gradient elution liquid chromatography (LC) coupled to mass spe...
This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray i...
This work reports the first on-chip generation of gradient elution using electrochemical pumping, fo...
A microfluidic device capable of two-dimensional reversed-phase liquid chromatography-capillary elec...
A microfluidic chip that integrates all the fluidic components of a gradient liquid chromatography (...
A gradient system was developed for the separation of proteins on a femtoliter scale utilizing nanof...
Integrated liquid chromatography (LC) chips are valued because of their significant advantages over ...
A new free-flow electrophoresis microchip with integrated permeable membranes was developed, and dif...
The lab-on-a-chip concept has enabled miniature instruments to be developed that allow the rapid exe...
A technique of handling fluids at the submillimeter scale, microfluidics, plays an important role in...
A microfluidic device for pH gradient chromatofocusing is presented, which performs creation of a mi...
A new analytical technique, gradient chromatofocusing-mass spectrometry (gCF-MS), was developed empl...
We report here an integrated on-chip sample dispensing system for Electrospray Ionization-Mass Spect...
A microfabricated device has been developed in which electrospray ionization is performed directly f...
Seminal bioanalytical technologies for high-throughput analysis, such as flow cytometry and capillar...
Changes in liquid composition during gradient elution liquid chromatography (LC) coupled to mass spe...
This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray i...
This work reports the first on-chip generation of gradient elution using electrochemical pumping, fo...
A microfluidic device capable of two-dimensional reversed-phase liquid chromatography-capillary elec...
A microfluidic chip that integrates all the fluidic components of a gradient liquid chromatography (...
A gradient system was developed for the separation of proteins on a femtoliter scale utilizing nanof...
Integrated liquid chromatography (LC) chips are valued because of their significant advantages over ...
A new free-flow electrophoresis microchip with integrated permeable membranes was developed, and dif...
The lab-on-a-chip concept has enabled miniature instruments to be developed that allow the rapid exe...
A technique of handling fluids at the submillimeter scale, microfluidics, plays an important role in...
A microfluidic device for pH gradient chromatofocusing is presented, which performs creation of a mi...
A new analytical technique, gradient chromatofocusing-mass spectrometry (gCF-MS), was developed empl...
We report here an integrated on-chip sample dispensing system for Electrospray Ionization-Mass Spect...
A microfabricated device has been developed in which electrospray ionization is performed directly f...
Seminal bioanalytical technologies for high-throughput analysis, such as flow cytometry and capillar...
Changes in liquid composition during gradient elution liquid chromatography (LC) coupled to mass spe...