Huntington\u27s Disease and Stem Cells

Huntington\u27s Disease (HD) is a progressive neurodegenerative disease with significant psychiatric and physical effects. We first began by implementing cell passaging procedures with both embryonic stem cells (ESCs) and neural stem cells (NSCs). Further, my thesis includes a synopsis of prior research to date regarding the overview of HD and epidemiology. Finally, in this study we use neural stem cells (NSCs) as a model of HD. The Huntingtin in one cell lines contains 140 glutamine repeats (140Q) while the “wildtype” control cells are 7Q. Our results conclude the difference between a healthy and HD-affected NSC