New approaches to treat bacterial infections are badly needed to address the increasing problem of antibiotic resistance. This study explores phosphonium-functionalized block copolymer micelles as intrinsically antibacterial polymer assemblies. Phosphonium cations with varying alkyl lengths were conjugated to the terminus of a poly(ethylene oxide)− polycaprolactone block copolymer, and the phosphonium-functionalized block copolymers were self-assembled to form micelles in aqueous solution. The size, morphology, and ζ -potential of the assemblies were studied, and their abilities to kill Escherichia coli and Staphylococcus aureus were evaluated. It was found that the minimum bactericidal concentration depended on the phosphonium alkyl chain ...
Synthetic amphiphilic polymers have been established as potentially efficient agents to combat wides...
The combination of state-of-the-art polymerization chemistries, post-polymerization chemical modific...
Crystallization-driven self-assembly (CDSA) was employed for the preparation of monodisperse cationi...
There is currently an urgent need for the development of new antibacterial agents to combat the spre...
The global health threat of antimicrobial resistance has created a pressing need to develop practica...
The development of new approaches to antibacterial surfaces is of growing interest to combat the spr...
Synthetic amphiphilic polymers have been established as potentially efficient agents to combat wides...
Bacterial infections have become a global issue that requires urgent attention, particularly regardi...
In view of the growing worldwide rise in microbial resistance, there is considerable interest in des...
Infections caused by multidrug-resistant bacteria are on the rise and, therefore, new antimicrobial ...
We demonstrate that antibacterial activity can be conferred to common plastic materials using amphip...
Bacterial infection is one of the most challenging problems in the biomedical field. A long list of ...
Over the last decade, polymer micelles and nanoparticles have attracted an increasing interest as ef...
Over the last decade, polymer micelles attracted an increasing interest in drug pharmaceutical resea...
With conventional antibiotic therapies being increasingly ineffective, bacterial infections with sub...
Synthetic amphiphilic polymers have been established as potentially efficient agents to combat wides...
The combination of state-of-the-art polymerization chemistries, post-polymerization chemical modific...
Crystallization-driven self-assembly (CDSA) was employed for the preparation of monodisperse cationi...
There is currently an urgent need for the development of new antibacterial agents to combat the spre...
The global health threat of antimicrobial resistance has created a pressing need to develop practica...
The development of new approaches to antibacterial surfaces is of growing interest to combat the spr...
Synthetic amphiphilic polymers have been established as potentially efficient agents to combat wides...
Bacterial infections have become a global issue that requires urgent attention, particularly regardi...
In view of the growing worldwide rise in microbial resistance, there is considerable interest in des...
Infections caused by multidrug-resistant bacteria are on the rise and, therefore, new antimicrobial ...
We demonstrate that antibacterial activity can be conferred to common plastic materials using amphip...
Bacterial infection is one of the most challenging problems in the biomedical field. A long list of ...
Over the last decade, polymer micelles and nanoparticles have attracted an increasing interest as ef...
Over the last decade, polymer micelles attracted an increasing interest in drug pharmaceutical resea...
With conventional antibiotic therapies being increasingly ineffective, bacterial infections with sub...
Synthetic amphiphilic polymers have been established as potentially efficient agents to combat wides...
The combination of state-of-the-art polymerization chemistries, post-polymerization chemical modific...
Crystallization-driven self-assembly (CDSA) was employed for the preparation of monodisperse cationi...