In Vivo and in Vitro Studies of Anaplasma Marginale in Non-bovine Cells

Anaplasma marginale is a Rickettsia-like organism that has been studied extensively since 1893. This research project was designed to investigate in vitro transmission of marginal bodies from infected bovine erythrocytes to uninfected cervid erythrocytes and from infected cervid erythrocytes to uninfected bovine erythrocytes. Four experiments were conducted to help illustrate this transmission phenomena. In addition, an experiment involving infected splenectomized, uninfected splenectomized, infected intact and uninfected intact white-tailed deer was designed to help illustrate parasitemia percentages, hematocrit values, complement-fixation titers and the course of infection in each experimental white-tailed deer model.Veterinary Parsitolog