Pharmacokinetics of Sulfachlorpyridazine in Channel Catfish (Ictalurus Punctatus)

Fish culture, a growing industry, has increased the demand for therapeutic agents. Due to the lack of pharmacokinetic studies in fish, the use of effective antibacterial agents are either based on studies in other animals or prohibited by FDA. This study was undertaken to gain an understanding of the pharmacokinetics of the antimicrobial agent, sulfachlorpyridazine (SCP) in fish. Comparison of the pharmacokinetics of this drug with other well studied groups of animal were expected to provide evidence for or against the potential usefulness of SCP as a therapeutic agent for catfish.Physiological Sciences (Pharmacology