Pharmacokinetics of Gentamicin in Channel Catfish (Ictalurus Punctatus)

This study uses the channel catfish as a poikilothermic model with which the pharmacokinetics of the aminoglycoside antibiotic, gentamicin, could be studied. The primary objectives of this study are to establish reliable pharmacokinetic parameters on which a rational course of antibiotic therapy can be based and to determine the effectiveness and reliability of selected enteral and parenteral routes of administration.Physiological Science