The axonal coupling to the glia matrix was hypothesized to contribute to the transition from non-affine (independent) to affine (interdependent) behavior of axonal kinematics. The effect of spinal cord growth on axonal kinematic behavior was investigated with a chick embryo spinal cord model. Chick spinal cords at different development stage (E12, E14, E16, and E18) were stretched to different levels (0, 5, 10, 15, and 20%). The tortuosity distribution of axons at each developmental stage and each stretch level was characterized. Axonal deformation showed increasing coupled behavior with development and growth. The experimental results did not follow ideal affine nor non-affine behavior. A 'switching' model was then employed and the values ...
Functional motor performance is dependent upon the correct assemblage of neural circuitry, a process...
Neuronal differentiation is under the tight control of both biochemical and physical information ari...
AbstractIn order to elucidate the mechanisms regulating the projections of dorsal root ganglion (DRG...
International audienceFluorescent lipophilic dyes are an ideal tool to study axonal pathfinding. Bec...
ABSTRACT Whether the axonal framework is stationary or moves is a central debate in cell biology. To...
The mechanical properties of the spinal cord dictate its response to traumatic loading conditions, a...
Neuronal growth is a complex process involving many intra- and extracellular mechanisms which are co...
Motor axon outgrowth to the hindlimb of the chick embryo is constrained by two barrier tissues that ...
To improve the quality of life for victims of traumatic spinal cord and brain injury, a better und...
AbstractWhether the axonal framework is stationary or moves is a central debate in cell biology. To ...
A considerable challenge confronts, any developing neuron. Before it can establish a functional and ...
AbstractAxonal interactions, which are mediated by cell adhesion molecules (CAMs) as well as other t...
International audienceNeuronal differentiation is under the tight control of both biochemical and ph...
AbstractWe have tested whether the orientation of axons sprouting from bipolar dorsal root ganglion ...
Tissue transplantation methods, previously used to study neural develop-ment, myelination and inheri...
Functional motor performance is dependent upon the correct assemblage of neural circuitry, a process...
Neuronal differentiation is under the tight control of both biochemical and physical information ari...
AbstractIn order to elucidate the mechanisms regulating the projections of dorsal root ganglion (DRG...
International audienceFluorescent lipophilic dyes are an ideal tool to study axonal pathfinding. Bec...
ABSTRACT Whether the axonal framework is stationary or moves is a central debate in cell biology. To...
The mechanical properties of the spinal cord dictate its response to traumatic loading conditions, a...
Neuronal growth is a complex process involving many intra- and extracellular mechanisms which are co...
Motor axon outgrowth to the hindlimb of the chick embryo is constrained by two barrier tissues that ...
To improve the quality of life for victims of traumatic spinal cord and brain injury, a better und...
AbstractWhether the axonal framework is stationary or moves is a central debate in cell biology. To ...
A considerable challenge confronts, any developing neuron. Before it can establish a functional and ...
AbstractAxonal interactions, which are mediated by cell adhesion molecules (CAMs) as well as other t...
International audienceNeuronal differentiation is under the tight control of both biochemical and ph...
AbstractWe have tested whether the orientation of axons sprouting from bipolar dorsal root ganglion ...
Tissue transplantation methods, previously used to study neural develop-ment, myelination and inheri...
Functional motor performance is dependent upon the correct assemblage of neural circuitry, a process...
Neuronal differentiation is under the tight control of both biochemical and physical information ari...
AbstractIn order to elucidate the mechanisms regulating the projections of dorsal root ganglion (DRG...