Porìvnâl'ne doslìžennâ fìzìologìčnoï aktivnostì vodi Naftusâ Truskavec'kogo ì Pomìrec'kogo rodoviŝ

The monography is devoted to studying the influence of bioactive water Naftussya as natural adaptogen on pathogenic and sanogenic manifestations of stress. In an experiment on rats of both sexes showed that preventive weekly consumption Naftussya as Truskavets’ and Pomyarky deposits minimizes caused by acute immobilization cold stress erosive and ulcerative damages of gastric mucosa and pathogenic changes in 10 parameters of neuroendocrine-immune complex and metabolism and prevents abnormalities yet 5 indicators, but does not affect post stressory pathogenic deviation 7 other parameters. However, bioactive water Naftussya increases or initiates compensatory and sanogene effects of stress, aimed at enhancing the antimicrobial protection. In clinical-physiological monitoring of individuals of both sexes with dysfunction of neuro-endocrine-immune complex as a manifestation of chronic stress found that weekly consumption Naftussya normalizes initially raised: Baevskiy’s activity of regulatory systems index, markers as sympathetic and vagal tone as well as testosterone in women, while initially normal levels of testosterone in men falls into the bottom zone rules. Lowering within the standards area also found on triiodothyronine. On the other hand, found a slight increase in the normal levels of aldosterone and post occlusive systolic blood pressure reactivity as well as tend to increase within the low reactive anxiety. Regarding the parameters of quantitative electroencephalography first discovered normalizing increase initially reduced spectral power density (SPD) α-rhythm in loci T6, P4 and F7, increase in the normal modal frequency β-rhythm and further enhance SPD θ-rhythm in the locus T5. On the other hand, showed a reduction in the initial normal SPD β-rhythm in locus O2 and further reduce its in locus P4. In addition, there was left-sided lateralization initially symmetric α-rhythm. Regarding the immune status for the first time found that Naftussya significantly increases to normal the reduced options phagocytosis by neutrophils of blood as gram-positive and gram-negative bacteria. This increased initially normal levels of T-killers and "active" T-lymphocytes, normalized reduced levels of circulating immune complexes and increased levels of immunoglobulins M and A, and elevated levels of natural killer cells to continue growing. In general, the effect on the neuroendocrine-immune complex is physiologically favorable. Among the metabolic parameters discovered that Naftussya increases within the normal plasma levels of chloride and sodium, normalizes low levels of bicarbonate and reduces in the normal levels of potassium and phosphates. Urinary excretion of sodium and chloride increases while of uric acid decreases which lowers its concentration, as the concentration of phosphates. Increased lithogeniciti index of urine normalized. Reduced levels of triacylglycerides increases, while decreases in the normal level of cholesterol in low-density lipoprotein composition. Among the biophysical parameters first detected increase in the normal conductivity acupuncture points Pg(ND) right, which represents the nervous system and increase electrokinetic index of buccal epithelium, indicating the "rejuvenation" of the body. For the first time identified changes in gas discharge visualization parameters, namely the elimination of asymmetries virtual chakras (second, third and first) and reducing excess energy of the first chakra. No significant differences between the effects water Naftussya both deposits were found. A comparative study of immediate effects in men with dysfunction of the neuro-endocrine-immune complex by discriminant analysis selected 38 indicators. In their totality the complex conditions in the basal period and after 1,5 hours after consuming the control waters (distilled, from the well and filtered water) and waters Naftussya (from Pomyarky, Truskavets’ and Skhidnytsya deposits) significantly differ, whereas no significant differences between control and basic water were found. Thus, the bioactive water Naftussya 1,5 h after ingestion causes changes in the neuro-endocrine-immune complex, different from both the initial level and the control. Received priority data about stress limiting effects of bioactive water Naftussya Pomyarky field in experiment on rats and its immediate and long-term effects on neuroendocrine-immune complex and water and electrolyte exchange in patients with dysfunction of the neuroendocrine-immune complexes together with known data of physical, chemical and bacteriological studies give reason to believe the water closest analogue of bioactive water Naftussya Truskavets’ deposit and recommend to include it in the balneologic arsenal spa Truskavets’