Genome wide conditional mouse knockout resources.
- Kaloff, C.
- Anastassiadis, K.
- Ayadi, A.
- Baldock, R.
- Beig, J.
- Birling, M.C.
- Bradley, A.
- Brown, S.D.M.
- Bürger, A.
- Bushell, W.
- Chiani, F.
- Collins, F.S.
- Doe, B.
- Eppig, J.T.
- Finnell, R.H.
- Fletcher, C.
- Flicek, P.
- Fray, M.
- Friedel, R.H.
- Gambadoro, A.
- Gates, H.
- Hansen, J.
- Herault, Y.
- Hicks, G.G.
- Hörlein, A.
- Hrabě de Angelis, M.
- Iyer, V.
- de Jong, P.J.
- Koscielny, G.
- Kühn, R.
- Liu, P.
- Lloyd, K.C.K.
- Lopez, R.G.
- Marschall, S.
- Martínez, S.
- McKerlie, C.
- Meehan, T.F.
- von Melchner, H.
- Moore, M.
- Murray, S.A.
- Nagy, A.
- Nutter, L.M.J.
- Pavlovic, G.
- Pombero, A.
- Prosser, H.
- Ramirez-Solis, R.
- Ringwald, M.
- Rosen, B.
- Rosenthal, N.
- Rossant, J.
- Ruiz Noppinger, P.
- Ryder, E.
- Skarnes, W.C.
- Schick, J.
- Schnütgen, F.
- Schofield, P.
- Seisenberger, C.
- Selloum, M.
- Smedley, D.
- Simpson, E.M.
- Stewart, A.F.
- Teboul, L.
- Tocchini Valentini, G.P.
- Valenzuela, D.
- West, A.P.
- Wurst, W.
DOIAbstract
© 2017 Elsevier Ltd. The International Knockout Mouse Consortium (IKMC) developed high throughput gene trapping and gene targeting pipelines that produced mostly conditional mutations of more than 18,500 genes in C57BL/6N mouse embryonic stem (ES) cells which have been archived and are freely available to the research community as a frozen resource. From this unprecedented resource more than 6000 mutant mouse strains have been generated by the IKMC in collaboration with the International Mouse Phenotyping Consortium (IMPC). In addition, a cre-driver resource was established including 250 C57BL/6 cre-inducible mouse strains. Complementing the cre-driver resource, a collection comprising 27 rAAVs expressing cre in a tissue-specific manne...
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