Posttranscriptional gene regulation is of great importance for a range of cellular functions. The active transport of transcripts and their local translation presents a mechanism important for embryo- and neurogenesis, neuronal plasticity, and stem cell differentiation. Impaired localization of transcripts result in erroneous embryogenesis, defective cell division, and neurological diseases. The DFG Research Unit FOR2333 has been established to mechanistically understand the processes of mRNA localization
International audienceIntracellular targeting of mRNAs has long been recognized as a means to produc...
mRNA localisation coupled to translational regulation provides an important means of dictating when ...
Summary: Faithful cellular differentiation requires temporally precise activation of gene expression...
Die asymmetrische Verteilung von mRNA und Proteinen innerhalb einer Zelle definiert die Polarität. ...
Post-transcriptional control of mRNA trafficking and metabolism plays a critical role in the actuali...
AbstractmRNA subcellular distribution and translational control are key player mechanisms for post-t...
RNA localization and translational control are crucial for cellular fine-tuning of gene expression i...
AbstractLocalization of RNA is a widespread and efficient way to target gene products to a specific ...
The elaborate morphology of neurons together with the information processing that occurs in remote d...
The elaborate morphology of neurons together with the information processing that occurs in remote d...
The intracellular localization of mRNA is an important mechanism for targeting proteins to their sit...
Neurons are morphologically complex cells that rely on the compartmentalization of protein expressio...
Messenger RNA plays a central role in gene expression. Regulation of gene expression is critical to ...
Control of mRNA translation and localization plays an important role in many developmental contexts....
International audienceIntracellular targeting of mRNAs has long been recognized as a means to produc...
International audienceIntracellular targeting of mRNAs has long been recognized as a means to produc...
mRNA localisation coupled to translational regulation provides an important means of dictating when ...
Summary: Faithful cellular differentiation requires temporally precise activation of gene expression...
Die asymmetrische Verteilung von mRNA und Proteinen innerhalb einer Zelle definiert die Polarität. ...
Post-transcriptional control of mRNA trafficking and metabolism plays a critical role in the actuali...
AbstractmRNA subcellular distribution and translational control are key player mechanisms for post-t...
RNA localization and translational control are crucial for cellular fine-tuning of gene expression i...
AbstractLocalization of RNA is a widespread and efficient way to target gene products to a specific ...
The elaborate morphology of neurons together with the information processing that occurs in remote d...
The elaborate morphology of neurons together with the information processing that occurs in remote d...
The intracellular localization of mRNA is an important mechanism for targeting proteins to their sit...
Neurons are morphologically complex cells that rely on the compartmentalization of protein expressio...
Messenger RNA plays a central role in gene expression. Regulation of gene expression is critical to ...
Control of mRNA translation and localization plays an important role in many developmental contexts....
International audienceIntracellular targeting of mRNAs has long been recognized as a means to produc...
International audienceIntracellular targeting of mRNAs has long been recognized as a means to produc...
mRNA localisation coupled to translational regulation provides an important means of dictating when ...
Summary: Faithful cellular differentiation requires temporally precise activation of gene expression...