Insulin activity is an important laboratory parameter in the clinical evaluation of several diseases such as diabetes mellitus types I and II, states of impaired glucose tolerance, and insulin-producing tumors (insulinomas), where the insulin secretion released from pancreas β-cells is altered
OBJECTIVE: Maintenance ofnormal glucose tolerance is achieved in subjects with a wide range of insul...
<p>Time course of (<b>A</b>) plasma insulin concentration (pM), and (<b>B</b>) plasma glucose (mM) i...
The feedback loops between glucose and insulin have as fundamental a role in diabetes as do the regu...
In the absence of sufficiently sensitive methods for the chemical determination of insulin, attempts...
Pancreatic β-cells are responsible for the synthesis and exocytosis of insulin in response to an inc...
The feasibility of investigating glucose tolerance and insulin action and secretion in vivo in mouse...
The impaired insulin secretion and increased insulin resistance (or decreased insulin sensitivity) p...
Defective insulin secretion plays a crucial role in insulin-dependent (Type 1) and non-insulin-depen...
The metabolic activity of insulin has been studied extensively in vitro and in vivo, based on the in...
<p>SI is the insulin stimulation index i.e. incremental folds above baseline insulin release. Result...
Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a r...
Obesity and dyslipidemia are often found in association with insulin resistance (IR). These componen...
Plasma glucose and insulin concentrations have been used in genetic studies as quantitative phenotyp...
Various methods have been proposed to assess insulin action in vivo, from the most complex to the si...
Insulin action is crucial for the regulation of glucose metabolism. Insulin plays a key role in supp...
OBJECTIVE: Maintenance ofnormal glucose tolerance is achieved in subjects with a wide range of insul...
<p>Time course of (<b>A</b>) plasma insulin concentration (pM), and (<b>B</b>) plasma glucose (mM) i...
The feedback loops between glucose and insulin have as fundamental a role in diabetes as do the regu...
In the absence of sufficiently sensitive methods for the chemical determination of insulin, attempts...
Pancreatic β-cells are responsible for the synthesis and exocytosis of insulin in response to an inc...
The feasibility of investigating glucose tolerance and insulin action and secretion in vivo in mouse...
The impaired insulin secretion and increased insulin resistance (or decreased insulin sensitivity) p...
Defective insulin secretion plays a crucial role in insulin-dependent (Type 1) and non-insulin-depen...
The metabolic activity of insulin has been studied extensively in vitro and in vivo, based on the in...
<p>SI is the insulin stimulation index i.e. incremental folds above baseline insulin release. Result...
Insulin resistance is a pathophysiological state defined by impaired responses to insulin and is a r...
Obesity and dyslipidemia are often found in association with insulin resistance (IR). These componen...
Plasma glucose and insulin concentrations have been used in genetic studies as quantitative phenotyp...
Various methods have been proposed to assess insulin action in vivo, from the most complex to the si...
Insulin action is crucial for the regulation of glucose metabolism. Insulin plays a key role in supp...
OBJECTIVE: Maintenance ofnormal glucose tolerance is achieved in subjects with a wide range of insul...
<p>Time course of (<b>A</b>) plasma insulin concentration (pM), and (<b>B</b>) plasma glucose (mM) i...
The feedback loops between glucose and insulin have as fundamental a role in diabetes as do the regu...
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