Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past few years, but our understanding of the genetic basis of T2D in ethnically diverse populations remains limited. We performed a genome-wide association study and a replication study in Chinese Hans comprising 8,569 T2D case subjects and 8,923 control subjects in total, from which 10 single nucleotide polymorphisms were selected for further follow-up in a de novo replication sample of 3,410 T2D case and 3,412 control subjects and an in silico replication sample of 6,952 T2D case and 11,865 control subjects. Besides confirming seven established T2D loci (CDKAL1, CDKN2A/B, KCNQ1, CDC123, GLIS3, HNF1B, and DUSP9) at genome-wide significance, we id...
AIMS/HYPOTHESIS: Most genetic variants identified for type 2 diabetes have been discovered in Europe...
Background: Recent genome-wide association studies (GWASs) have reported several genetic variants to...
Type 2 diabetes (T2D) has become a major health problem throughout the world and the epidemic is par...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
This is the final version of the article. Available from the American Diabetes Association via the D...
This study aimed to examine genomic loci of type 2 diabetes (T2D) initially identified by genome-wid...
Most genetic variants identified for type 2 diabetes have been discovered in European populations. W...
[[abstract]]Bcakground: A recent genome-wide association study for type 2 diabetes in Han Chinese id...
Background A recent genome-wide association study for type 2 diabetes in Han Chinese identified seve...
This study aimed to examine genomic loci of type 2 diabetes (T2D) initially identified by genome-wid...
Most genetic variants identified for type 2 diabetes have been discovered in European populations. W...
Aims/hypothesisCandidate gene and genome-wide association studies have identified ∼60 susceptibility...
AIMS/HYPOTHESIS: Most genetic variants identified for type 2 diabetes have been discovered in Europe...
Background: Recent genome-wide association studies (GWASs) have reported several genetic variants to...
Type 2 diabetes (T2D) has become a major health problem throughout the world and the epidemic is par...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
Substantial progress has been made in identification of type 2 diabetes (T2D) risk loci in the past ...
This is the final version of the article. Available from the American Diabetes Association via the D...
This study aimed to examine genomic loci of type 2 diabetes (T2D) initially identified by genome-wid...
Most genetic variants identified for type 2 diabetes have been discovered in European populations. W...
[[abstract]]Bcakground: A recent genome-wide association study for type 2 diabetes in Han Chinese id...
Background A recent genome-wide association study for type 2 diabetes in Han Chinese identified seve...
This study aimed to examine genomic loci of type 2 diabetes (T2D) initially identified by genome-wid...
Most genetic variants identified for type 2 diabetes have been discovered in European populations. W...
Aims/hypothesisCandidate gene and genome-wide association studies have identified ∼60 susceptibility...
AIMS/HYPOTHESIS: Most genetic variants identified for type 2 diabetes have been discovered in Europe...
Background: Recent genome-wide association studies (GWASs) have reported several genetic variants to...
Type 2 diabetes (T2D) has become a major health problem throughout the world and the epidemic is par...