This study deals with the question of whether mouse bone marrow-derived mast cells are able to produce interleukin-6 (IL-6) in vitro. For this purpose, a panel of primary mast cell clones from limiting-dilution microcultures, of permanent IL-3-dependent mast cell lines and autonomous malignant sublines, was screened. All of these lines were found to produce growth factor activity for IL-6-dependent mouse hybridoma cells (7TD1), which could be completely neutralized by the monoclonal anti-IL-6-antibody 6B4. Transcriptional activity of the IL-6 gene was demonstrated in both IL-3-dependent mast cells and autonomous sublines using a mouse IL-6-specific cDNA probe
We explored the molecular mechanisms involved in the establishement of CMA-03/06, an IL-6-independen...
IL-6 is a multifunctional cytokine involved in differentiation and proliferation of immune cells. Mo...
<div><p>Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and hos...
This study deals with the question of whether mouse bone marrow-derived mast cells are able to produ...
A series of murine interleukin 3 (IL-3)-dependent hemopoietic cell lines was studied for the capacit...
A series of murine interleukin 3 (IL-3)-dependent hemopoietic cell lines was studied for the capacit...
A novel mast cell growth-enhancing activity (MEA/P40/interleukin 9 [IL-9]) purified from the conditi...
A series of permanent IL-3-dependent cell lines have been established from normal BALB/c or C3H bone...
Murine interleukin 3 (IL-3)-dependent permanent mast cell lines derived from normal mouse bone marro...
Since mast cells and basophils are thought to play a central role in several types of cutaneous infl...
Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and inc...
Interleukin (IL)-3-dependent mouse bone marrow-derived mast cells (BMMCs) are an important model for...
(A) BMDM from Il6rafl/fl×LysMcre and Il6rafl/fl control mice were differentiated with IL-4 or LPS + ...
Stem cell factor (SCF) and interleukin-3 (IL-3) both act on several target hematopoietic populations...
Mouse bone marrow-derived mast cells (mBMMCs) are an invaluable tool for the study of mast cell func...
We explored the molecular mechanisms involved in the establishement of CMA-03/06, an IL-6-independen...
IL-6 is a multifunctional cytokine involved in differentiation and proliferation of immune cells. Mo...
<div><p>Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and hos...
This study deals with the question of whether mouse bone marrow-derived mast cells are able to produ...
A series of murine interleukin 3 (IL-3)-dependent hemopoietic cell lines was studied for the capacit...
A series of murine interleukin 3 (IL-3)-dependent hemopoietic cell lines was studied for the capacit...
A novel mast cell growth-enhancing activity (MEA/P40/interleukin 9 [IL-9]) purified from the conditi...
A series of permanent IL-3-dependent cell lines have been established from normal BALB/c or C3H bone...
Murine interleukin 3 (IL-3)-dependent permanent mast cell lines derived from normal mouse bone marro...
Since mast cells and basophils are thought to play a central role in several types of cutaneous infl...
Radiation-induced L8313 leukemia hearing mice of Yoshida and Seki show marked granulocytosis and inc...
Interleukin (IL)-3-dependent mouse bone marrow-derived mast cells (BMMCs) are an important model for...
(A) BMDM from Il6rafl/fl×LysMcre and Il6rafl/fl control mice were differentiated with IL-4 or LPS + ...
Stem cell factor (SCF) and interleukin-3 (IL-3) both act on several target hematopoietic populations...
Mouse bone marrow-derived mast cells (mBMMCs) are an invaluable tool for the study of mast cell func...
We explored the molecular mechanisms involved in the establishement of CMA-03/06, an IL-6-independen...
IL-6 is a multifunctional cytokine involved in differentiation and proliferation of immune cells. Mo...
<div><p>Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and hos...