Sequencing of multiple clostridial genomes related to biomass conversion and biofuel production.
- Hemme, C.L.
- Mouttaki, H.
- Lee, Y.J.
- Zhang, G.
- Goodwin, L. Lucas, S.
- Copeland, A.
- Lapidus, A.
- Glavina Del Rio, T.
- Tice, H.
- Saunders, E.
- Brettin, T.
- Detter, J.C.
- Han, C.S.
- Pitluck, S.
- Land, M.L.
- Hauser, L.J.
- Kyrpides, N.
- Mikhailova, N.
- He, Z.
- Wu, L.
- van Nostrand, J.D.
- Henrissat, B.
- He, Q.
- Lawson, P.A.
- Tanner, R.S.
- Lynd, L.R.
- Wiegel, J.
- Fields, M.W.
- Arkin, A.P.
- Schadt, C.W.
- Stevenson, B.S.
- McInerney, M.J.
- Yang, Y.
- Dong, H.
- Xing, D.
- Ren, N.
- Wang, A.
- Huhnke, R.L.
- Mielenz, J.R.
- Ding, S.Y.
- Himmel, M.E.
- Taghavi, S.
- van der Lelie, D.
- Rubin, E.M.
- Zhou, J.
DOIAbstract
Modern methods to develop microbe-based biomass conversion processes require a system-level understanding of the microbes involved. Clostridium species have long been recognized as ideal candidates for processes involving biomass conversion and production of various biofuels and other industrial products. To expand the knowledge base for clostridial species relevant to current biofuel production efforts, we have sequenced the genomes of 20 species spanning multiple genera. The majority of species sequenced fall within the class III cellulosome-encoding Clostridium and the class V saccharolytic Thermoanaerobacteraceae. Species were chosen based on representation in the experimental literature as model organisms, ability to degrade cellulosic...
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