Folic acid has been frequently exploited for target therapies geared toward overexpressed folate receptors on malignant cells. The folic acid/folate-receptor high affinity interaction can be used to not only target but image cancer cells. Folate-linked nanoparticles represent a potential new drug carrier for tumor cell-selective therapeutics. Folate targeting, nanoparticles in therapeutics, and cancer cell imaging will be outlined in this literature report
Conventional chemotherapeutic approaches in cancer therapy such as surgery, chemotherapy, and radiot...
Conventional cancer treatment methods suffer from many limitations such as non-specificity and low e...
The way of viewing cancer has advanced considerably in the last few decades because of recent progre...
Targeted drug therapy or “smart” drug delivery, potentially combined with simultaneous imaging modal...
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer the...
In normal tissues, the expression of folate receptors is low and limited to cells that are important...
The discovery of high levels of the folate receptor (FR) on human tumor cells has rendered this fola...
Molecular imaging (MI) of cancer is an emerging field in diagnostic imaging that provides means for ...
Discovery and development of folic acid based receptor targeting started in late 1991 and early 1992...
Folate receptor (FR) is highly expressed in many types of human cancers, and it has been actively st...
Folate receptor (FR) is well known for its overexpression on surface of various cancer cell lines, w...
The discovery of the high-affinity, high-specificity folate receptor in mamalian kidney cells, coupl...
Over-expression of folate receptor alpha on cancer cells has been frequently exploited for delivery ...
The folate receptor (FR) is a GPI anchored cell surface glycoprotein that functions to facilitate fo...
Folate receptor-targeted imaging agents have previously been utilized to image and diagnose both can...
Conventional chemotherapeutic approaches in cancer therapy such as surgery, chemotherapy, and radiot...
Conventional cancer treatment methods suffer from many limitations such as non-specificity and low e...
The way of viewing cancer has advanced considerably in the last few decades because of recent progre...
Targeted drug therapy or “smart” drug delivery, potentially combined with simultaneous imaging modal...
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer the...
In normal tissues, the expression of folate receptors is low and limited to cells that are important...
The discovery of high levels of the folate receptor (FR) on human tumor cells has rendered this fola...
Molecular imaging (MI) of cancer is an emerging field in diagnostic imaging that provides means for ...
Discovery and development of folic acid based receptor targeting started in late 1991 and early 1992...
Folate receptor (FR) is highly expressed in many types of human cancers, and it has been actively st...
Folate receptor (FR) is well known for its overexpression on surface of various cancer cell lines, w...
The discovery of the high-affinity, high-specificity folate receptor in mamalian kidney cells, coupl...
Over-expression of folate receptor alpha on cancer cells has been frequently exploited for delivery ...
The folate receptor (FR) is a GPI anchored cell surface glycoprotein that functions to facilitate fo...
Folate receptor-targeted imaging agents have previously been utilized to image and diagnose both can...
Conventional chemotherapeutic approaches in cancer therapy such as surgery, chemotherapy, and radiot...
Conventional cancer treatment methods suffer from many limitations such as non-specificity and low e...
The way of viewing cancer has advanced considerably in the last few decades because of recent progre...