Chapter one of this dissertation gives an overview of the isolation and structure determination of nodulisporic acids and details their biological activity. Then the optimization of the synthetic sequence leading to the Eastern Hemisphere Subtarget of Nodulisporic Acids A, D and F is described.* Chapter two gives a detailed account of the development of a new modular indole synthesis using a sequential Stille cross-coupling/Buchwald-Hartwig Union/Cyclization tactic. The new modular indole synthesis was successfully applied for the preparation of several highly substituted and strained indoles, including the CDEF parent tetracycle of Nodulisporic Acids A and B.* *Please refer to dissertation for diagrams
A convergent total synthesis of the architecturally complex indole diterpenoid (−)-nodulisporic acid...
This two-part dissertation describes total syntheses of (-)-indolizidine 223AB and alkaloid (-)-205B...
Development of novel synthetic methodologies and their application to synthesis of natural products ...
Chapter one of this dissertation gives an overview of the isolation and structure determination of n...
Chapter one of this dissertation provides a general introduction to the indole diterpenoid class of ...
The dissertation herein presents efforts toward the synthesis of the potent insecticidal indole dite...
The first total syntheses of architecturally complex indole terpenes (−)-nodulisporic acid D and (−)...
The first total syntheses of architecturally complex indole terpenes (–)-nodulisporic acid D and (–)...
The first total syntheses of architecturally complex indole terpenes (–)-nodulisporic acid D and (–)...
(+)-Nodulisporic Acid A (NsAA) is an indole diterpene of complex structure, isolated from the fungus...
The dissertation herein presents efforts toward the synthesis of the potent insecticidal indole dite...
The nodulisporic acids comprise a subclass of the paxilline indole diterpene family and express pote...
Chapter one discusses the previous use of synthetic chemistry in biosynthetic studies of natural pro...
In Chapter 1, a thorough overview of the paxilline indoloterpenoids will be covered with an emphasis...
A short, enantioselective synthesis of (-)-nodulisporic acid C is described. The route features two ...
A convergent total synthesis of the architecturally complex indole diterpenoid (−)-nodulisporic acid...
This two-part dissertation describes total syntheses of (-)-indolizidine 223AB and alkaloid (-)-205B...
Development of novel synthetic methodologies and their application to synthesis of natural products ...
Chapter one of this dissertation gives an overview of the isolation and structure determination of n...
Chapter one of this dissertation provides a general introduction to the indole diterpenoid class of ...
The dissertation herein presents efforts toward the synthesis of the potent insecticidal indole dite...
The first total syntheses of architecturally complex indole terpenes (−)-nodulisporic acid D and (−)...
The first total syntheses of architecturally complex indole terpenes (–)-nodulisporic acid D and (–)...
The first total syntheses of architecturally complex indole terpenes (–)-nodulisporic acid D and (–)...
(+)-Nodulisporic Acid A (NsAA) is an indole diterpene of complex structure, isolated from the fungus...
The dissertation herein presents efforts toward the synthesis of the potent insecticidal indole dite...
The nodulisporic acids comprise a subclass of the paxilline indole diterpene family and express pote...
Chapter one discusses the previous use of synthetic chemistry in biosynthetic studies of natural pro...
In Chapter 1, a thorough overview of the paxilline indoloterpenoids will be covered with an emphasis...
A short, enantioselective synthesis of (-)-nodulisporic acid C is described. The route features two ...
A convergent total synthesis of the architecturally complex indole diterpenoid (−)-nodulisporic acid...
This two-part dissertation describes total syntheses of (-)-indolizidine 223AB and alkaloid (-)-205B...
Development of novel synthetic methodologies and their application to synthesis of natural products ...