Add to ORKGThe dissertation contained herein presents a total synthesis of (-)-enigmazole A utilizing a late-stage large-fragment Petasis-Ferrier union/rearrangement protocol. Chapter One details the isolation, structural elucidation and subsequent biological studies of (-)-enigmazole A. The previous synthetic studies of (-)-enigmazole A are also introduced. The chapter then outlines the Smith three-step Petasis-Ferrier union/rearrangement protocol, as well as a number of the successful total syntheses achieved over the years by the Smith group utilizing this protocol. Herein, a late-stage large-fragment Petasis-Ferrier union/rearrangement will be utilized as the synthetic cornerstone for the Smith total synthesis of (-)-enigmazole A. Chapter Two desc...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
This thesis describes the Smith group\u27s synthetic efforts toward the tedanolides, marine natural ...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.Vita. Cataloged fro...
The dissertation contained herein presents a total synthesis of (–)-enigmazole A utilizing a late-st...
Studies toward the total synthesis of (–)-enigmazole B are presented in the dissertation contained h...
Enigmazole A and its congeners, isolated form the sponge Cinachyrella enigmatica, are the first know...
A highly convergent, stereocontrolled total synthesis of the architecturally complex marine sponge m...
Total synthesis of (−)-enigmazole B was achieved for the first time. Highlights of the present synth...
This dissertation describes the total synthesis of the potent anticancer agent (+)-phorboxazole A (1...
The dissertation describes the total synthesis of (+)-largazole, the development of multicomponent r...
An efficient entry into the phosphorylated marine macrolide enigmazole A is described. Enigmazole A ...
This dissertation describes synthetic studies culminating in the total synthesis of the potent antip...
This dissertation describes synthetic studies culminating in the first total synthesis of the potent...
This dissertation describes the synthetic studies culminating in the Smith total synthesis of (+)-te...
This dissertation describes progress towards the synthesis of spirastrellolide E, a potent cytotoxic...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
This thesis describes the Smith group\u27s synthetic efforts toward the tedanolides, marine natural ...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.Vita. Cataloged fro...
The dissertation contained herein presents a total synthesis of (–)-enigmazole A utilizing a late-st...
Studies toward the total synthesis of (–)-enigmazole B are presented in the dissertation contained h...
Enigmazole A and its congeners, isolated form the sponge Cinachyrella enigmatica, are the first know...
A highly convergent, stereocontrolled total synthesis of the architecturally complex marine sponge m...
Total synthesis of (−)-enigmazole B was achieved for the first time. Highlights of the present synth...
This dissertation describes the total synthesis of the potent anticancer agent (+)-phorboxazole A (1...
The dissertation describes the total synthesis of (+)-largazole, the development of multicomponent r...
An efficient entry into the phosphorylated marine macrolide enigmazole A is described. Enigmazole A ...
This dissertation describes synthetic studies culminating in the total synthesis of the potent antip...
This dissertation describes synthetic studies culminating in the first total synthesis of the potent...
This dissertation describes the synthetic studies culminating in the Smith total synthesis of (+)-te...
This dissertation describes progress towards the synthesis of spirastrellolide E, a potent cytotoxic...
The application of the [2,3] Wittig rearrangement to the total synthesis of (+)-discodermolide is th...
This thesis describes the Smith group\u27s synthetic efforts toward the tedanolides, marine natural ...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.Vita. Cataloged fro...