Purpose: To identify the genomic location of previously uncharacterized canine retina-expressed expressed sequence tags (ESTs), and thus identify potential candidate genes for heritable retinal disorders. Methods: A set of over 500 retinal canine ESTs were mapped onto the canine genome using the RHDF5000–2 radiation hybrid (RH) panel, and the resulting map positions were compared to their respective localization in the CanFam2 assembly of the canine genome sequence. Results: Unique map positions could be assigned for 99% of the mapped clones, of which only 29% showed significant homology to known RefSeq sequences. A comparison between RH map and sequence assembly indicated some areas of discrepancy. Retinal expressed genes were not concentr...
Purpose: To facilitate the molecular characterization of naturally occurring cataracts in dogs by pr...
We performed transcriptome sequencing of canine retinal tissue by 454 GS-FLX and Ion Torrent PGM pla...
Abstract Background Dogs have the second largest number of genetic diseases, after humans. Among the...
Purpose: To identify the genomic location of previously uncharacterized canine retina-expressed expr...
International audiencePURPOSE: To identify the genomic location of previously uncharacterized canine...
Purpose: To identify the genomic location of previously uncharacterized canine retina-expressed expr...
Maps of the canine genome are now developing rapidly. Most of the markers on the current inte-grated...
Canine progressive retinal atrophies (PRA) are a group of hereditary diseases characterised by rod a...
Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-famil...
Progressive retinal degenerations are among the most common causes of blindness both in human and in...
Cataracts are the leading cause of blindness and low vision throughout the world. Millions of people...
As the thesis contains real data and those data is still being used in the process of further confir...
Purpose: To identify the causative mutation of canine progressive retinal atrophy (PRA) segregating ...
Considerable clinical and molecular variations have been known in retinal blinding diseases in man a...
International audienceRetinitis pigmentosa (RP) is a heterogeneous group of inherited retinal disord...
Purpose: To facilitate the molecular characterization of naturally occurring cataracts in dogs by pr...
We performed transcriptome sequencing of canine retinal tissue by 454 GS-FLX and Ion Torrent PGM pla...
Abstract Background Dogs have the second largest number of genetic diseases, after humans. Among the...
Purpose: To identify the genomic location of previously uncharacterized canine retina-expressed expr...
International audiencePURPOSE: To identify the genomic location of previously uncharacterized canine...
Purpose: To identify the genomic location of previously uncharacterized canine retina-expressed expr...
Maps of the canine genome are now developing rapidly. Most of the markers on the current inte-grated...
Canine progressive retinal atrophies (PRA) are a group of hereditary diseases characterised by rod a...
Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-famil...
Progressive retinal degenerations are among the most common causes of blindness both in human and in...
Cataracts are the leading cause of blindness and low vision throughout the world. Millions of people...
As the thesis contains real data and those data is still being used in the process of further confir...
Purpose: To identify the causative mutation of canine progressive retinal atrophy (PRA) segregating ...
Considerable clinical and molecular variations have been known in retinal blinding diseases in man a...
International audienceRetinitis pigmentosa (RP) is a heterogeneous group of inherited retinal disord...
Purpose: To facilitate the molecular characterization of naturally occurring cataracts in dogs by pr...
We performed transcriptome sequencing of canine retinal tissue by 454 GS-FLX and Ion Torrent PGM pla...
Abstract Background Dogs have the second largest number of genetic diseases, after humans. Among the...