Obesity is a growing disorder in the United States, affecting over 60% of the population. We previously defined sympathetic nervous system (SNS) outflow from brain to white adipose tissue (WAT) using a viral transneuronal tract tracer. SNS innervation of WAT is the principle initiator of lipolysis, whereas decreases in sympathetic drive promote lipid accumulation. Which of the many origins of SNS outflow from brain to WAT results in SNS-mediated changes in lipid mobilization (increases in drive) or accumulation (decrease in drive) is unknown. Previous research indicates that sympathetic denervation blocks lipid mobilization; thus, rostral sites in the neuroaxis connected to WAT via the SNS may promote WAT lipid mobilization. The hypothalami...
The rising prevalence of obesity poses a significant public health challenge, with profound implicat...
The balance of lipogenesis and lipolysis in fat tissue is regulated both by the interaction of blood...
For the past few decades, obesity has emerged as one of the major complex diseases affecting human ...
Obesity is a growing disorder in the United States, affecting over 60% of the population. We previou...
Summary: The melanocortin system is a brain circuit that influences energy balance by regulating ene...
Important players in triglyceride (TG) metabolism include the liver (production), white adipose tiss...
Abstract Important players in triglyceride (TG) metabolism include the liver (production), white adi...
Objective: Crosstalk between adipocytes and local neurons may be an important regulatory mechanism t...
Restricted until 24 July 2010.Insulin resistance is a major risk factor for the development of type ...
The wealth of clinical epidemiological data on the association between intra-abdominal fat accumulat...
We investigated a possible role of the central glucagon-like peptide (GLP-1) receptor system as an e...
More than 30% of the population suffers from obesity, which increases the risk of death and secondar...
Part of the results presented in this thesis were published in the following reference (DOI 10.1016/...
White adipose tissue (WAT) secretes factors to communicate with other metabolic organs to maintain e...
The sympathetic nervous system (SNS) plays an essential role in the regulation of metabolic and card...
The rising prevalence of obesity poses a significant public health challenge, with profound implicat...
The balance of lipogenesis and lipolysis in fat tissue is regulated both by the interaction of blood...
For the past few decades, obesity has emerged as one of the major complex diseases affecting human ...
Obesity is a growing disorder in the United States, affecting over 60% of the population. We previou...
Summary: The melanocortin system is a brain circuit that influences energy balance by regulating ene...
Important players in triglyceride (TG) metabolism include the liver (production), white adipose tiss...
Abstract Important players in triglyceride (TG) metabolism include the liver (production), white adi...
Objective: Crosstalk between adipocytes and local neurons may be an important regulatory mechanism t...
Restricted until 24 July 2010.Insulin resistance is a major risk factor for the development of type ...
The wealth of clinical epidemiological data on the association between intra-abdominal fat accumulat...
We investigated a possible role of the central glucagon-like peptide (GLP-1) receptor system as an e...
More than 30% of the population suffers from obesity, which increases the risk of death and secondar...
Part of the results presented in this thesis were published in the following reference (DOI 10.1016/...
White adipose tissue (WAT) secretes factors to communicate with other metabolic organs to maintain e...
The sympathetic nervous system (SNS) plays an essential role in the regulation of metabolic and card...
The rising prevalence of obesity poses a significant public health challenge, with profound implicat...
The balance of lipogenesis and lipolysis in fat tissue is regulated both by the interaction of blood...
For the past few decades, obesity has emerged as one of the major complex diseases affecting human ...