Add to ORKGA new extension of the Birch-Cope sequence is described which allows the efficient enantioselective construction of highly functionalized, fused bicarbocyclic structures with an all-carbon quaternary stereo-center in two steps. The two-step sequence includes a cross metathesis between a terminal alkene and a polarized alkene followed by an intramolecular Rauhut-Currier reaction with a trialkylphosphine catalyst
Thesis advisor: James P. MorkenDetailed within this dissertation are three new reactions involving a...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary c...
Criss‐cross catalysis: H. Zhao, J. F. Hartwig and co‐workers have combined homogeneous alkene metath...
The Birch reduction – alkylation is an effective way to form all-carbon quaternary centers from inex...
A new enantioselective desymmetrizing Mizoroki–Heck reaction is reported. The process affords high y...
Novel phenanthridinone analogues with an all-carbon quaternary stereocenter have been enantioselecti...
A novel three step asymmetric annulation procedure comprises a tandem catalytic enantioselective 1,4...
Due to the profound extent to which natural products inspire medicinal chemists in drug discovery, t...
Herein is reported an enantio- and diastereoselective tandem double borylation/1,2-addition of alkyn...
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks conta...
A novel three step asymmetric annulation procedure comprises a tandem catalytic enantioselective 1,4...
grantor: University of TorontoCycloalkenes bearing a quaternary carbon center were synthes...
This thesis describes the efforts of Professor James Leighton and myself toward the synthesis of the...
A copper/phosphoramidite catalyzed asymmetric allylic alkylation of Z trisubstituted allyl bromides ...
Quaternary carbon centres are ubiquitous in nature, typically in natural products. The task of crea...
Thesis advisor: James P. MorkenDetailed within this dissertation are three new reactions involving a...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary c...
Criss‐cross catalysis: H. Zhao, J. F. Hartwig and co‐workers have combined homogeneous alkene metath...
The Birch reduction – alkylation is an effective way to form all-carbon quaternary centers from inex...
A new enantioselective desymmetrizing Mizoroki–Heck reaction is reported. The process affords high y...
Novel phenanthridinone analogues with an all-carbon quaternary stereocenter have been enantioselecti...
A novel three step asymmetric annulation procedure comprises a tandem catalytic enantioselective 1,4...
Due to the profound extent to which natural products inspire medicinal chemists in drug discovery, t...
Herein is reported an enantio- and diastereoselective tandem double borylation/1,2-addition of alkyn...
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks conta...
A novel three step asymmetric annulation procedure comprises a tandem catalytic enantioselective 1,4...
grantor: University of TorontoCycloalkenes bearing a quaternary carbon center were synthes...
This thesis describes the efforts of Professor James Leighton and myself toward the synthesis of the...
A copper/phosphoramidite catalyzed asymmetric allylic alkylation of Z trisubstituted allyl bromides ...
Quaternary carbon centres are ubiquitous in nature, typically in natural products. The task of crea...
Thesis advisor: James P. MorkenDetailed within this dissertation are three new reactions involving a...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary c...
Criss‐cross catalysis: H. Zhao, J. F. Hartwig and co‐workers have combined homogeneous alkene metath...